According to recent studies, Risks Against Patient Safety (RAPS) represent one of the most important factors of dead in hospitals: during therapy, more then 8% of patients recovered in hospitals suffer for additional disease that in almost 50% of the cases produce either dead or significant additional health problems. RAPS occur in any stage of the patient care process.REMINE project idea originates from the common difficulty in conducting a analysis, early identification and effective prevention on RAP when there are significant mass of inhomogeneous data sources, stored in multimedia databases, and a distributed environments with different care professionals contemporary involved.To contrast the RAPS trends and the malpractices diffusion, REMINE prosecutes a number of main objectives. a new technological platform, new care process organizational requirements. Main elements are: mining of multimedia data; modeling, prediction, detection of RAPS, RAPS management support system and info broker patient safety framework.Main outcomes of REMINE will be: time reduction in collecting data, time reduction in RAPS analysis, standardization of common language, evolution in the interaction model, reference framework, patient safety improvement, health care cost saving (within an estimated RAPS reduction between 6% to 9% of RAPS.