The HEALTH IMPULSE project will develop bi-border regional centres of research and treatment of rare AID by utilizing cutting-edge technology as fully individualized innovative approach. The main objective of the project is to develop collaborative cross-border innovative research activities and services between MEFOS and PTE in the field of applied immunology (emphasis on rare autoimmune diseases), in order to increase the joint RDI capacity of our border regions and accessibility of the RDI products to the final users: patients and health care providers. Achievements: Another in a series of joint research efforts of the two knowledge centres in the region, the project was run by the Osijek and Pécs medical faculties and focused on the fi eld of applied immunology, specifi cally on rare autoimmune diseases. The primary goal of the project was to connect the experts dealing with the subject in the area and to provide them with a platform to share their ideas, fi ndings and research results and ultimately to develop standardised protocols for the management of diseases, furthermore to come up with potential diagnostic procedures applicable in the whole region.