Description The MobiGuide project has developed an intelligent decision-support system for patients with chronic illnesses, such as cardiac arrhythmias, diabetes and high blood pressure. The patient wears sensors that can monitor biosignals (e.g. heart rate, blood pressure); these signals are transmitted to their smartphone and from there to a powerful "backend" computer. The MobiGuide decision-support tool, which also has access to the patient's' historical clinical data, such as their hospital records, analyses the data and alerts the patient about actions that should be taken. It asks the patient questions, in case additional information is needed. The system also makes recommendations regarding lifestyle changes or contacting care providers. All recommendations regarding therapy are transmitted to the patients' care providers. The recommendations are based on evidence- based, state-of-the-art clinical guidelines. During the project the experts intend to focus on the following clinical conditions: atrial fibrillation, gestational diabetes and gestational hypertension.