The objective of the ManuCloud project is the development of the service-oriented IT infrastructure “ManuCloud” as basis for the next level of manufacturing networks by enabling inter-enterprise integration down to shop floor level. R&D Approach The ManuCloud IT infrastructure will consist of a set of services providing knowledge-based product specification based on the actual available manufacturing capabilities of the network, inter- enterprise data exchange, and inter-enterprise quality assurance. Additionally a highly agile intra-fab integration environment capable to automatically propagate manufacturing capabilities and manufacturing process data to the ManuCloud infrastructure will be developed. ManuCloud aims at bringing impact in the broad field of industrial manufacturing. Therefore ManuCloud does not targeting a specific industry, the concept will be applicable to all types of networked manufacturing. Impact and relevance of the project for a specific use case, but also in general, will be demonstrated by an industrial proof-of-concept. Industrial relevance is guaranteed by involving a strong industrial European key player, the Robert Bosch AG, as driver of the development and as end-user . The company has lately entered the photovoltaic industry and is actually investing in multiple companies in this domain. Several manufactures of innovative organic semiconductors are taking part in the project and will serve as testbed for the proof-of-concept ACP-IT and nxtControl will provide their knowledge in shop floor IT technologies. The scientific relevance is ensured by bringing together leading European institutes from the manufacturing engineering and automation, the organic semiconductor manufacturing, the supply chain management, the knowledge-based product specification domain and their implementation in applications.