Aim: to systematically inform city policy makers & decision takers of the relative cost-effectiveness of different types of investments by municipalities and their partners in shaping the lifestyle of the community (proximal determinants) and thus reducing the level and burden of disease.Objective 1, to enhance and transfer to European cities an innovative modelling tool, designed to predict the impact of population level risk reduction on the cost of acute CHD related hospital admissions and death rates over a five-year period. The enhanced model will be used to assess the impact of City level investments in six domains (of housing, economy, environment, education, security and health) on lifestyle issues and subsequently on risk level and the burden of disease.Objective 2, To jointly develop with partners and transfer an innovative Vocational and Educational Training (VET) Programme, designed for professionals, technicians and politicians in each domain public, to facilitate the use of the risk assessment tool in the decision making process in City policy planning and investment decisions.