In view of current developments in the fields of porous materials and discrete nano-sized molecules and aggregates the lack of organometallic-based compounds acting as nodes together with functionalized organic linkers in such materials and as linkers and building blocks for nano-sized spheres and aggregates is obvious. By using organometallic polyphosphorus compounds it was possible to synthesize unprecedented prototypes of such materials and molecular nano-sized superspheres. These ground-breaking discoveries will be subsequently further developed to excess a qualitatively novel level of research by using polypnictogen starting materials. Key targets will be the generation of rigid 3D organometallic-based materials, discrete supramolecular nano-sized aggregates (charged moiety approach) and novel fullerene-like supramolecules as nano-spheres, nano-capsules and nano-wheels (neutral moiety approach). Especially the latter approach will generate unprecedented spheres and molecules which are extreme in size and function as there are multifunctional binding sites; multi-magnetic properties; tuning templates in size; generating, encapsulating and releasing highly reactive intermediates and reaction components. Finally, the work will move beyond our knowledge of known structurally characterized fullerenes by the development of non-carbon based alternatives within and beyond the fullerene topology.