Over the past years, the EU has funded several projects that undertook research on specific integrated water resources management (IWRM) issues in case studies carried out on twinned river basins from Europe and from developing countries. The aim of Twin2Go now is to review, assess, synthesize and consolidate the outcomes of these projects in order to make them transferable and applicable to other basins, and to disseminate the project results effectively to relevant authorities, stakeholders and end-users. This will contribute to the overall goal to underpin the implementation of IWRM in line with the targets of the EU Water Initiative. In order to achieve this aim, Twin2Go will elaborate a methodology that allows comparative analysis and synthesis of the outcomes of the diverse projects. The consolidated outcomes will feed into best practice guidelines for the adoption and implementation of sustainable water resources management plans. To ensure up-take of the research results in water resources management practice and political decision making, all synthesis activities will involve stakeholders from the projects and basins and synthesis results will be effectively disseminated to all relevant levels of target groups including high level decision makers in water policy. In its effort, Twin2Go will focus its activities on the thematic priority ‘adaptive water governance in the context of climate change’ and cluster past and ongoing twinning projects along their target regions (Latin America, Africa, NIS, South and South East Asia). Through its co-ordinating activities, Twin2Go will bring together participants and lead partners from past and ongoing projects as well as international water networks. This will allow increasing the output and benefit of ongoing research by consolidating results, exploiting synergies and thus build up the critical mass that will promote uptake of research results and reaching audiences at a higher level of decision making.