The aim of METABO is to set up a comprehensive platform, running both in clinical settings and in every-day life environments, for continuous and multi-parametric monitoring of the metabolic status in patients with, or at risk of, diabetes and associated metabolic disorders.The type of parameters that will be monitored, in addition to traditional clinical and biomedical parameters, will also include subcutaneous glucose concentration, dietary habits, physical activity and energy expenditure, effects of ongoing treatments, and autonomic reactions.The data produced by METABO will be integrated with the clinical data and the history of the patient and will be used in two major interrelated contexts of care:1.\tSetting up a dynamic model of the metabolic behavior of the individual to predict the influence and relative impact of specific treatments and of single parameters on glucose level.2.\tBuilding personalized care plans integrated in the current clinical processes linking the different actors in primary and secondary care and improving the active role of the Patient.