NIMBLE: collaboration Network for Industry, Manufacturing, Business and Logistics in Europe will develop the infrastructure for a cloud-based, Industrie 4.0, Internet-of-things-enabled B2B platform on which European manufacturing firms can register, publish machine-readable catalogs for products and services, search for suitable supply chain partners, negotiate contracts and supply logistics, and develop private and secure B2B and M2M information exchange channels to optimise business work flows. The infrastructure will be developed as open source software under an Apache-type, permissive license. The governance model is a federation of platforms for multi-sided trade, with mandatory interoperation functions and optional added-value business functions that can be provided by third parties. This will foster the growth of a net-centric business ecosystem for sustainable innovation and fair competition as envisaged by the Digital Agenda 2020. Prospective NIMBLE providers can take the open source infrastructure and bundle it with sectoral, regional or functional added value services and launch a new platform in the federation. Internet platforms need fast adoption rates and the work plan reflects this: we start attracting early adopters from day one and develop the initial, working platform in year one. Added-value business functions follow in year two and final validation at large scale, involving hundreds of external firms, will happen in year three. Our adoption plan is designed to enable two or more platform providers at the end of the project, and to have 1000 to 2000 enterprises connected to the overall ecosystem at that point. NIMBLE has 17 partners grouped around 3 main activities: developing the infrastructure, running a platform adoption programme, and validating the platform with 4 supply chains (white goods, wooden houses, fashion fabrics, and child care furniture). NIMBLE will give manufacturing SMEs in Europe a stable and sustainable digital ecosystem.