Description HYDROBIONETS designs the world's first real-time micro-biological wireless networked The HYDROBIONETS project focuses on the research and development of Self-Organized Wireless BioMEM Networks (WBNs) and their integration in a global system to monitor the complete water cycle in large-scale water treatment and desalination plants. The key feature is the integration of BioMEM sensors and actuators in motes and the adaptation of the network function to the specific requirements that this type of application imposes. The WBNs will achieve a distributed monitoring of critical parameters, representing a novel instrument that can be successfully applied in a short term to the great challenge that represents the dense wireless networked control of microbiological parameters of water in the different stages of process in these plants. A world-class interdisciplinary team formed by materials, sensors, microsystems, communications, signal processing, control and networking experts, as well as end-users, has been assembled to investigate, develop and validate the WBNs. This is a novel and ambitious approach in the field of microbiological water monitoring and control where several different disciplines converge.