Description Health and lifestyle monitoring of people with chronic diseases at a European level. The project developed for example a smart T-shirt to monitor and help the chronically illChronic diseases are the leading causes of death and disability for a large amount of people in most industrialized nations.  Chronic diseases have also a deep impact on today’s society costs. Adopting healthy behaviours can prevent or control the devastating effects of these diseases. CHRONIOUS implements a system architecture that offers continuous monitoring easily adaptable to any chronic disease management programme.The project goals will be achieved by developing a  modular and flexible system design that integrates state of the art sensors and services in order to cover both patients and healthcare professional’s needs.Data will be collected by using monitoring sensors, mostly wearable, that control continuously vital signals, dietary habits and plans, drug intake, environmental parameters, biochemical parameters, activity and social context.Every abnormal health condition will be noticed and reported by the system. In particular the CHRONIOUS system will report deviations and all conditions differing from those that are expected. Healthcare professionals on the other hand will be provided with supporting decision support and data analysis tools.CHRONIOUS, in its very final form, will be a universal solution to healthcare facilities and professionals for managing all different kind of chronic diseases increasing the quality of patients’ life and reducing health assistance costs.