Thanks to the developments in Medical Imaging Diagnosis is earlier than ever. Physicians have more information and insight. Care is less invasive and less painful for patients. Access to tests and treatments is easier as imaging procedures are available in convenient settings, such as independent imaging centers. In addition, patient outcomes— from fewer complications to saved lives—are dramatically improved.And we are not at the end of our journey, yet!. The “Next Generation” of Medical Imaging is just here out of the integration and cross-disciplinary use of NanoMedicine, Pharmacological breakthroughs, Biotechnologies for healthcare and ICT combined with standard Medical Imaging evolution.Unfortunately, the healthcare sector is quite diverse and collaboration has been difficult as a result, so the challenge is to build expertise in the development of integrated systems that address unmet clinical needs while providing a solid and consistent network of R&D + Innovation groups. Co-ordination and integration of Research-Driven Clusters under the so called “Triple Helix III approach is a must in order to achieve the growth and competitiveness opportunities that Advanced Medical Imaging brings to the European society.AMI-4EUROPE is to co-ordinate, integrate and set up a newly defined EU-based Value Chain on Advanced, Cross-disciplinary and Integrated Medical Imaging by taking full advantage of all strengths that European stakeholders have while targeting the market niches that are arising as the Next Generation Medical Imaging unfolds itself out of the convergence of Nanomedicine, Pharmaceutical and Biotechnologies for healthcare and taking advantage of the ICT developments.Socio-economic impact at European level will be significant.Sustainability and synergy-searching are assured: Many regional governments are backing up AMI-4EUROPE.