The project Adaptive Medical Profession Assessor (Med-Assess) has been funded as an innovation transfer project in the context of the LEONARDO DA VINCI call Lifelong Learning Programme (2012-2014). The developed solution of OntoHR (www.ontohr.eu) has been transferred from the IT domain to the health domain as well as from the Netherlands and Hungary to Germany, while still staying as a multi-lingual solution. Health sectors across Europe demand highly qualified nurses. The key to determine quality of nursing performance is determined as the ability and skills for applying domain specific knowledge in various situations properly. Nursing education is strongly tailored to on-the-job training and learning by doing. To fill existing knowledge gaps, nurses need to participate in (continual) vocational education and training (e.g. workshops or online courses). Med-Assess, supports (i) assessing of work-based competences and job knowledge of nurses, (ii) indicating existing knowledge gaps, and (iii) ultimately providing recommendations for improving nursing competences. The ontological approach of Med-Assess reinforces analysis and assessment of nursing job knowledge. It matches the nursing requirements and domain specific knowledge, and provides the logic for assessment of the end-users i.e. job applicants, nurses and care-givers. The solution is adaptable for different medical qualification areas. This way each potential clinic will be able to create individual Med-Assess measuring Knowledge-Bases i.e. neuroscience, internal medicine, sport medicine, etc.