Search for European Projects

11 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Nanomedicine upscaling for early clinical phases of multimodal cancer therapy (NoCanTher)

Start date: Apr 1, 2016, End date: Mar 31, 2021,

During the last four years the Multifun Consortium (FP7 project Nº. 262943) has developed and validated distinct nanoformulations as therapeutic approach against pancreatic and breast cancer. These nanoformulations are based on magnetic iron oxide nanoparticles (MNP) multifuntionalised with a target peptide and an anticancer chemical drug, allowing for a synergistic therapeutic effect produced by ...
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 13

 FINISHED 

Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease: Comparative Effectiveness Research of Existing Technologies (DISCHARGE)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

Coronary artery disease (CAD) is the leading cause of death in high-income countries. Invasive coronary angiography (ICA) is the reference standard for the diagnosis of CAD and allows immediate therapy. However, only 40% of patients undergoing ICA actually have obstructive CAD and ICA has relatively rare but considerable risks. Coronary computed tomography (CT) is the most accurate diagnostic test ...
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 38

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Advanced spectroscopic hemogram for personalized care against live threatening infections using an integrated chip-assisted bio-photonic system (HEMOSPEC)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

Life threatening infectious diseases and sepsis are worldwide problems with high mortalities. In order to select optimal treatments for the highly heterogeneous group of sepsis patients and to reduce costs, novel multiplexed tools that better characterize the patient and its specific immune response are highly desired.In the novel project "HemoSpec" a multidisciplinary team develops - driven by th ...
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 8

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Impact of Prenatal Stress on BRAIN AGEing (BRAINAGE)

Start date: Mar 1, 2012, End date: Feb 28, 2017,

Healthy brain ageing is a major determinant of quality life-long health, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to life style and genetic factors, environmental influences in prenatal life have a major impact on brain ageing and age-associated brain disorders. We hypothesize that: (1) prenatal stress programs early brain ag ...
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 10

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European collaborative project on Targeted therapy in renal cell cancer: genetic and tumor-related biomarkers for response and toxicity (EuroTARGET)

Start date: Mar 1, 2011, End date: Aug 31, 2016,

Each year more than 63,000 new cases of kidney cancer are diagnosed in the European Union. Approx. 50% of all patients have metastasized renal cell cancer (mRCC) at presentation or develop metastases during follow-up. 5-year relative survival of mRCC has been extremely poor: between 5 and 10%. In the past few years, so-called targeted therapies that suppress angiogenesis have changed the clinical ...
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 15

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OSTEOIMMUNE - Unraveling the Interactions between the Immune System and Bone (OSTEOIMMUNE)

Start date: Jun 1, 2012, End date: May 31, 2016,

Inflammatory rheumatic diseases affect millions of European citizens causing chronic pain, disability and premature death. Curative treatments are lacking. Conventional research often focuses on one single organ system such as the bone or the immune system and. ignores interactions between organ systems. OSTEOIMMUNE is a supra-disciplinary training network that targets this gap by providing compre ...
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 12

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Multifunctional Nanotechnology for selective detection and Treatment of cancer (MULTIFUN)

Start date: Jun 13, 2011, End date: Jun 12, 2015,

The aim of the MultiFun consortium is to develop and validate a novel and minimally-invasive nanotechnology system to improve cancer diagnosis and treatment. MultiFun nanotechnology is based on multifunctionalised magnetic nanoparticles to selectively target and eliminate breast and pancreatic cancer (stem) cells. The improved magnetic features of the MultiFun magnetic nanoparticles will lead to p ...
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 19

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Profiling Responders In Antibody Therapies (PRIAT)

Start date: Nov 1, 2012, End date: Oct 31, 2014,

"Therapeutic antibodies are the largest and fastest growing class of pharmaceutical biotechnology products, with annual sales above 30 billion US$. In some cases, antibody products have revolutionized the management of patients, e.g. TNF-blocking antibodies in Arthritis or Rituxan in lymphoma. However, for most antibody therapies, only a subset of patients benefit from treatment. Thus, there is an ...
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 8

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Direct observation of ligand binding and channel gating on individual ligand-gated ion channels (Fluoropatch)

Start date: Apr 1, 2010, End date: Jun 30, 2013,

Understanding the dynamics of ligand-gated ion channels is essential for understanding synaptic processes and neuronal signal integration (neurotransmitter gated channels) and intracellular signalling (cyclic nucleotide gated channels). Here we will combine single molecule fluorescence detection, with single channel electrophysiology, to detect ligand-binding and follow subsequent channel gating s ...
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 1

 FINISHED 

Improvement in Postoperative PAIN OUTcome (PAIN-OUT)

Start date: Jan 1, 2009, End date: Dec 31, 2012,

The main objective of the proposed project is to develop and to validate a system for measurement and feedback of outcome quality and support of decision making. The project will be executed in the areas of postoperative pain management which serves as an example for other fields of medicine with a high variation of care. The project will provide the medical community with a unique, user-friendly ...
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 18

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Prenatal diagnosis – indices of fetal developmental disturbances enabled by advanced signal identification techniques (PRENATAL DIAGNOSIS)

Start date: May 15, 2009, End date: May 14, 2011,

"Fetal programming of mental and cardiovascular diseases by adverse prenatal environmental influences is a main issue of developmental medicine. However, the number of measurable functional parameters in the human fetus is limited. The assessment of key parameters of the underlying processes of fetal brain maturation could foster the early detection of developmental problems, the design of therape ...
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 1