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3 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Genetic interaction networks: From C. elegans to human disease (2-HIT)

Start date: Sep 1, 2008, End date: Apr 30, 2014,

"Most hereditary diseases in humans are genetically complex, resulting from combinations of mutations in multiple genes. However synthetic interactions between genes are very difficult to identify in population studies because of a lack of statistical power and we fundamentally do not understand how mutations interact to produce phenotypes. C. elegans is a unique animal in which genetic interactio ...
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Unraveling the mechanisms of odor coding and sent-tracking in Drosophila larvae (MnemoSmell)

Start date: Sep 1, 2008, End date: Aug 31, 2012,

To survive and prosper, any motile organism must extract relevant cues from its external environment and convert them into coherent internal representations. Responses elicited by the flow of internal representations form the basis of adaptive behaviours. The overall goal of this project is to elucidate how olfactory signalling and behavioural decisions emerge from the integration of molecular and ...
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The evolution of genetic robustness (2B-Robust)

Start date: Mar 1, 2008, End date: Feb 28, 2010,

Most genes are not required for viability. This robustness to mutation is a fundamental property of complex biological systems but the mechanism(s) underlying it and how it evolves is unclear. It has been proposed that robustness can result from genetic redundancy through gene duplication and the distributed nature of biological networks. The robustness of both yeast and C. elegans has been dissec ...
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