Search for European Projects

12 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Treatment of late onset bacterial sepsis caused by vancomycin susceptible bacteria in neonates and infants aged under three months (NEOVANC)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

Vancomycin is the critically important antibiotic to treat neonatal Late Onset Sepsis (LOS) due to Gram positive bacteria in neonates, including Coagulase Negative Staphylococci (CoNS) and Staphylococcus aureus. These organisms also create biofilms which are extremely resistant to antibiotics. The increased incidence of LOS due to bacteria such as CoNS and MRSA in NICUs has led to a marked increas ...
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 14

 FINISHED 

Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)

Start date: Dec 1, 2013, End date: Nov 30, 2018,

The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
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 10

 FINISHED 

Aggression subtyping for improved insight and treatment innovation in psychiatric disorders (AGGRESSOTYPE)

Start date: Nov 1, 2013, End date: Oct 31, 2018,

Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

 FINISHED 

Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment in children with difficult to treat Epilepsy (DESIRE)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

DESIRE will focus on epileptogenic developmental disorders EDD, i.e. early onset epilepsies whose origin is closely related to developmental brain processes. A major cause of EDD are malformations of cortical development (MCD), either macroscopic or subtle. EDD are often manifested as epileptic encephalopathies (EE), i.e. conditions in which epileptic activity itself may contribute to severe cogni ...
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 29

 FINISHED 

First Targeted Therapy to FIGHT Hemophagocytic Lymphohistiocytosis (HLH): A novel approach to HLH (FIGHT-HLH)

Start date: Jul 1, 2012, End date: Jul 31, 2017,

Hemophagocytic lymphohistiocytosis (HLH) is a rare, devastating disease characterized by uncontrolled immune response that primarily affects young infants and children. HLH is usually fatal if untreated. Even when treated, the overall survival rate is still as low as 60-70%. No drug has been formally developed for the treatment of this disease and current treatment methods require the use of drugs ...
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 6

 FINISHED 

Global Research in Paediatrics (GRiP)

Start date: Jan 1, 2011, End date: Jun 30, 2017,

Paediatric drugs (PD) lack appropriate testing. Most drugs have inadequate information about dosing regimen, dose adjustment and how to administer them. These are longstanding problems that unquestionably require concerted efforts at the international level. Both the US and the EU have introduced paediatric legislation that facilitates participation of children in research and pharmaceutical innov ...
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 24

 FINISHED 

Data-as-a-Service platform for Healthy Lifestyle and preventive medicine (DAPHNE)

Start date: Nov 1, 2013, End date: Oct 31, 2016,

Description Helping Europeans manage their weightIn some EU countries, about two in three adults and one in three children are overweight. With DAPHNE, researchers and businesses join forces to help people manage their weight and increase physical exercise using emerging technologies and information systems. The project will use a new gen ...
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 10

 FINISHED 

International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research (INTREALL)

Start date: Oct 1, 2011, End date: Sep 30, 2016,

Though survival of children with acute lymphoblastic leukaemia (ALL) has improved, relapse remains a leading cause of mortality in childhood cancer. Given the rarity of the disease, only a large international cooperative group can recruit sufficient patients for prospective studies with specific questions in biologic subgroups. Under the umbrella of the I-BFM SG all relevant mainly European study ...
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 29

 FINISHED 

Proof of Concept of Model-based Cardiovascular Prediction (CARDIOPROOF)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

CARDIOPROOF is a proof-of-concept project that consolidates the outcomes of previous VPH projects and checks the applicability and effectiveness of available predictive modelling and simulation tools, validating them in interrelated clinical trials conducted in three European centres of excellence in cardiac treatment (from Germany, Italy and the UK). CARDIOPROOF focuses on patients with aortic va ...
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 10

 FINISHED 

Advanced Cell-based Therapies for the treatment of Primary ImmunoDeficiency (CELL-PID)

Start date: Nov 1, 2010, End date: Apr 30, 2016,

Primary immune deficiencies (PID) are inherited disorders of the adaptive and innate immune system marked by severe infections, autoimmunity and high risk of cancer. Treatment entails hematopoietic stem cell (HSC) transplantation from allogeneic donors, however in the absence of an HLA compatible donor, HSCT outcome is limited by delayed or suboptimal reconstitution and complications. SCID-X1 and ...
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 20

 FINISHED 

Effective Perinatal Intensive Care in Europe: translating knowledge into evidence based practice (EPICE)

Start date: Jan 1, 2011, End date: Dec 31, 2015,

"Context: Very preterm infants face high risks of mortality and long-term neuro-developmental impairment. Rates of mortality and morbidity vary by a factor greater than two between European regions. This project’s overriding aim is to improve these infants’ survival and long-term health and development by ensuring that available medical knowledge is translated into effective perinatal care.Objecti ...
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 14

 FINISHED 

Written language processing in Hearing and Deaf (WoRHD)

Start date: Oct 1, 2008, End date: Sep 30, 2011,

An issue dominating the current debate in the field of written language processing concerns the existence of brain areas dedicated to the visual perception of words. Cohen et al. (2002) suggested that such visual specialization occurs in occipito-temporal region of the left hemisphere, namely at the ‘Visual Word Form Area’ (VWFA). Using Magnetoencephalography (MEG) and presenting words and anagram ...
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 2