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There is mounting evidence that the often ignored kinetic aspects of the interaction between a drug and its target are highly relevant for clinical success. This ignorance may be one of the reasons for the high attrition rates in drug discovery, as it has been analyzed that many recently marketed drugs had indeed improved kinetic profiles. This hindsight knowledge needs to be converted into data-d ...

Point-of-care testing is essential to provide better patient care by aiding physicians in making informed decision during patient visits. This will enable the start of immediate treatment for many conditions and reduce the strain on resources in secondary care, resulting in reduced outpatient clinic time. A key challenge in the development of point-of-care diagnostic devices is the requirement fo ...