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4 European Projects Found

Searched on 125080 European Projects

 FINISHED 

iABC Programme (IABC PROGRAMME)

Start date: Aug 1, 2015, End date: Jul 31, 2020,

Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon ...
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 21

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Cannabinoid receptors CB1 in schizophrenia: role of brain mitochondrial activity and astroglial signalling (SCHIZO-mtCB1)

Start date: Feb 1, 2015, End date: Jan 31, 2017,

"Schizophrenia is a severe psychiatric disorder characterized by a series of ""positive"" and ""negative"" symptoms, which eventually lead to strong sufferance, social isolation and occupational impairment. Via activation of type-1 cannabinoid receptors (CB1), cannabinoids are known to induce schizophrenic-like symptoms, which are major caveats in the possible therapeutic use of these compounds. O ...
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 1

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Characterization of the role of Scrib1 and Vangl2 in neuronal migration (MigPCP)

Start date: Mar 1, 2012, End date: Feb 28, 2015,

Although the cerebral cortex is responsible for all the intellectual life that makes us human, we know remarkably little about how this amazing structure is formed. We do know, however, that genetic conditions in which the cortex is not formed properly have devastating consequences. Neurological disorders are frequently associated with developmental brain malformations. Progress toward understandi ...
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 1

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Role of Rnd proteins in the regulation of dendrite, spine and synapse formation in the developing hippocampus and their implication in hippocampal-dependent memory (RhoHippoMemo)

Start date: Jul 2, 2012, End date: Jul 1, 2014,

The rapidly growing elderly population and the increasing occurrence of memory disorders make the promotion of “healthy ageing” and the treatment of these disorders a major challenge in our modern societies. However, the development of treatments is hindered mainly because the biological basis of memory is still unclear. For this reason a better understanding of the mechanisms regulating memory pr ...
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 1