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Abnormal heart rhythms are a major cause of cardiovascular disease and death in Europe. Sudden cardiac death accounts for 50% of cardiac mortality in developed countries; ventricular tachycardia or ventricular fibrillation is the commonest underlying arrhythmia. In the ambulatory population, atrial fibrillation is the commonest one, and is associated with increased risk of stroke and heart failur ...

Coronary artery disease (CAD) is caused by an accumulation of plaques within the walls of the arteries that supply the myocardium with oxygen and nutrients. After decades of progression, some of these plaques may rupture and along with the activation of the blood clotting system limit blood flow to the myocardium, resulting in an acute coronary syndrome (ACS). This may be either a heart attack (my ...