3 European Projects Found
Searched on 125080 European Projects
FINISHED
Model-based preclinical development of anti-tuberculosis drug combinations (PREDICT-TB)
Start date: May 1, 2012, End date: Oct 30, 2017,
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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23
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FINISHED
Training Network on Zebrafish Infection Models for Pharmaceutical Screens (FishForPharma)
Start date: Jan 1, 2012, End date: Dec 31, 2015,
Infectious diseases caused by pathogenic micro-organisms are major causes of death, disability, and social and economic disruption for millions of people. During evolution these pathogens have developed intricate strategies to manipulate host defence mechanisms and outwit the immune system. To reduce the burden of infectious diseases it is important to increase understanding of these host-pathogen ...
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10
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FINISHED
Developing high-thoughput bioassays for human cancers in zebrafish (ZF-CANCER)
Start date: Apr 1, 2008, End date: Mar 31, 2011,
"Recently the zebrafish has emerged as a new important system for cancer research because the zebrafish genome contains all orthologs of human oncogenes and forms tumors with similar histopathological and gene profiling features as human tumors. The zebrafish provides an in vivo vertebrate model for identifying novel mechanisms of cancer progression and for development of new anticancer compounds ...
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