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3 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic model of epilepsy – tuberous sclerosis complex (EPISTOP)

Start date: Nov 1, 2013, End date: Oct 31, 2018,

Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usual ...
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 FINISHED 

Multicentre Preclinical Animal Research Team (Multi-PART)

Start date: Sep 1, 2013, End date: Aug 31, 2015,

Millions of Europeans still suffer the consequences of neurological disease, but the number of new drugs coming to market continues to fall. Reasons for the failure of stroke drug efficacy to translate from animals to clinical trials is probably best studied, but the problem is widespread. The economic and social costs of translational failure are substantial; a new approach to translational medic ...
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 12

 FINISHED 

Mitochondrial dysfunction in neurodegenerative diseases: towards new therapeutics (Mitotarget)

Start date: Feb 1, 2009, End date: Mar 31, 2012,

Mitochondrial dysfunction is a major hallmark of various neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, Huntington’s diseases or Amyotrophic Lateral Sclerosis (ALS). However linking mitochondrial dysfunction to the pathogenesis of some of these diseases still needs to be elucidated. Furthermore, in pathologies where this link is already established, the question re ...
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