1 European Projects Found
Searched on 125080 European Projects
FINISHED
T cell receptor αβ : in control of signal initiation and T cell fate (TERRAINCOGNITA)
Start date: Apr 1, 2010, End date: Mar 31, 2015,
One of the central mysteries of immunology is self-tolerance. How does the human body select ~10e12 T lymphocytes, that are reactive to foreign pathogens but tolerant to normal cellular constituents of the host? Over the last few years, my laboratory identified 2 fundamental mechanisms used by thymocytes to establish T cell tolerance. We demonstrated that the affinity threshold for negative select ...
Read Project
