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"Bone marrow stromal cells (BMSCs) have been shown to be neuroprotective after experimental ischemic stroke when given systemically. By this route of administration, however, over 99% of cells are trapped in lung, spleen and kidneys. This off-target distribution of BMSCs may result in serious ectopic side-effects thereby making their use in humans questionable.The applicant’s previous work has dem ...
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"Cellular bioenergetics play a key role in the pathogenesis of acute and chronic neurological disorders. Novel sensors and analytical systems in combination with biomedical imaging can provide powerful new insights into the role of cellular bioenergetics in the propagation of disease states. OXY-SENSE is an Industry-Academia partnership of experienced neuroscientists, experts in optical oxygen sen ...
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