3 European Projects Found
Searched on 125080 European Projects
FINISHED
"Health and the Understanding of Metabolism, Aging and Nutrition" (HUMAN)
Start date: Oct 1, 2013, End date: Sep 30, 2018,
"Recently intense research identified around 4,000 single nucleotide polymorphisms (SNPs) associated with human age related diseases such as metabolic disorders. Despite their highly significant association to pathology, the functional role of these genetic variants is, in most cases, yet to be elucidated. The evolutionary distance of most animal models from humans represents a major limitation fo ...
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17
Partners Participants
FINISHED
Systems biology for the functional validation of genetic determinants of skeletal diseases (SYBIL)
Start date: Oct 1, 2013, End date: Sep 30, 2018,
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and transnational scientists, systems biologists, disease modellers, leading SMEs and industrialists that will perform in-depth char ...
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19
Partners Participants
FINISHED
Advanced Cell-based Therapies for the treatment of Primary ImmunoDeficiency (CELL-PID)
Start date: Nov 1, 2010, End date: Apr 30, 2016,
Primary immune deficiencies (PID) are inherited disorders of the adaptive and innate immune system marked by severe infections, autoimmunity and high risk of cancer. Treatment entails hematopoietic stem cell (HSC) transplantation from allogeneic donors, however in the absence of an HLA compatible donor, HSCT outcome is limited by delayed or suboptimal reconstitution and complications. SCID-X1 and ...
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