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 FINISHED 
"The goal of this project is to perform a European phase II clinical trial to demonstrate that PDGF-BB acts as a unique regenerative therapy for Parkinson’s Disease (PD), aimed at reversing the course of the disease, by promotion of endogenous brain repair mechanisms. Current pharmacological therapies for PD carry side-effects and become less effective as the disease progresses. This causes immen ...
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 FINISHED 

NOTCH SIGNALING IN DEVELOPMENT AND PATHOLOGY (NotchIT)

Start date: Jan 1, 2009, End date: Dec 31, 2012,

Eight partners from six different EU countries will converge in NotchIT, a multi-site ITN aimed to increase the knowledge of cellular and molecular mechanisms by which Notch signaling regulates the development and pathology of different tissues. Notch signaling plays a key role in cell-fate determination and differentiation of various cell types and aberrant Notch signaling is associated with path ...
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 11

 FINISHED 
Angiogenesis underlies almost all biological processes of morphogenesis, including those in tissue repair and regeneration. Physiological angiogenesis is controlled by a complex interplay between cells and their environment: the extracellular matrix (ECM) provides signaling via numerous ECM adhesion molecules and growth factors bound to ECM polysaccharide components; and cells locally degrade and ...
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