Search for European Projects

Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

...results unreliable or even impossible. To tackle this, SPIDA4P aims to generate and implement a comprehensive portfolio of 22 pan-European pre-analytical CEN/Technical Specifications and ISO/International Standards, addressing the important pre-analytical workflows applied to personalized medicine. These will also applicable to biomarker discovery, development and validation as well as to biobanks ...
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 21

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European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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 43

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Advanced solutions for assuring the overall authenticity and quality of olive oil (OLEUM)

Start date: Sep 1, 2016, End date: Aug 31, 2020,

...alibration of the sensory panels coupled with rapid screening tools to facilitate the work of the panelists. The most promising OLEUM solutions will be subjected to VALIDATION in conformity with internationally agreed standards by peer laboratories. OLEUM will recreate a realistic “deodorization scenario” by producing tailored, soft deodorized OOs by lab-scale and up-scaled pilot plants to apply a ...
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 24

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Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES) (BRIDGES)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths. Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery. Breast cancer risk is determined by a combination of genetic and lifestyle risk factors. The advent of next generation sequencing has opened up th ...
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 20

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Integrated and innovative key actions for mycotoxin management in the food and feed chain (MycoKey)

Start date: Apr 1, 2016, End date: Mar 31, 2020,

...along food and feed chains. The project will contribute to reduce mycotoxin contamination mainly in Europe and China, where frequent and severe mycotoxin contaminations occur in crops, and where international trade of commodities and contaminated batches are increasing. MycoKey will address the major affected crops maize, wheat and barley, their associated toxigenic fungi and related mycotoxins (a ...
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 32

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Combatting Bacterial Resistance in Europe - Carbapenem Resistance (COMBACTE-CARE)

Start date: Mar 1, 2015, End date: Feb 28, 2020,

...m-negative bacteria (MDR-GNB): the ultimate challenge!Antibiotic resistance is a global public health concern recently elevated to the top three threats identified by the WHO, and subject of numerous national and international government activities. Although focused strategies have beneficially influenced infection rates due to methicillin resistant Staphylococcus aureus (MRSA), infections due to ...
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 23

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European Gram Negative Antibacterial Engine (ENABLE)

Start date: Feb 1, 2014, End date: Jan 31, 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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 42

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Imaging the Force of Cancer (FORCE)

Start date: Jan 1, 2016, End date: Dec 31, 2019,

Cancer is the second leading cause of mortality in EU member states with ~90% of all cancer deaths caused by metastatic spread. Despite its significance, measuring metastatic potential as well as potential indicators of therapy efficacy remain unmet clinical challenges. Recently, it has been demonstrated in vitro, that aggressive metastatic cells pull on their surroundings suggesting that metastat ...
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 18

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European Initiative to Enable Validation for Highly Automated Safe and Secure Systems (ENABLE-S3)

Start date: May 1, 2016, End date: Apr 30, 2019,

ENABLE-S3 will pave the way for accelerated application of highly automated and autonomous systems in the mobility domains automotive, aerospace, rail and maritime as well as in the health care domain. Virtual testing, verification and coverage-oriented test selection methods will enable validation with reasonable efforts. The resulting validation framework will ensure Europeans Industry competiti ...
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 76

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TBVAC2020; Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)

Start date: Jan 1, 2015, End date: Dec 31, 2018,

...B vaccine and biomarker pipeline as well as accelerate development of most promising TB vaccine candidates through early development stages. The proposed approach and involvement of many internationally leading groups in the TB vaccine and biomarker area in TBVAC2020 fully aligns with the Global TB Vaccine Partnerships (GTBVP).
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 49

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RNA-based technologies for single-cell metabolite analysis (MetaRNA)

Start date: Jan 1, 2015, End date: Dec 31, 2018,

Metabolism is the foundation of all living organisms. While cells in a population are often phenotypically different, most of our current analytical approaches still probe metabolism only at the population level. Because strong evidence exists that metabolic cell-to-cell heterogeneity has, for instance, disease relevance, researcher from MetaRNA will overcome this severe analytical limitation thro ...
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 11

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Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Start date: Apr 1, 2016, End date: Mar 31, 2018,

...d the capabilities of the HBP Platforms, in order to use them to address otherwise intractable problems in neuroscience, computing and medicine in the future. In addition, collaborations with other national, European and international initiatives will create synergies, maximizing returns on research investment. SGA1 covers the detailed steps that will be taken to move the HBP closer to achieving i ...
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 126

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European Medical Information Framework (EMIF)

Start date: Jan 1, 2013, End date: Dec 31, 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

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European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)

Start date: Jan 1, 2012, End date: Dec 31, 2017,

ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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 48

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European Research Infrastructures for Poverty Related Diseases (EURIPRED)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

...e presents a prime opportunity to address other sexually transmitted diseases such as viral hepatitis efficiently and effectively. The overall goal of the EURIPRED is to coordinate and integrate international resources into a single specialised infrastructure to support European HIV, TB, Malaria and Hepatitis B virus and Hepatitis C virus studies from early drug, vaccine and microbicide discovery ...
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 18

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Advanced Immunization Technologies (ADITEC)

Start date: Oct 1, 2011, End date: Sep 30, 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

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European Initial Training Network on Developmental and Computational Biology (DevCom)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

The ability to manipulate cellular pluripotency and differentiation holds the as yet unrealized promise of regenerative medicine to produce replacement cells and tissues. To this end a deep understanding of the regulation of differentiation potential in the context of normal embryonic development is crucial. The recent revolution in sequencing technology has enabled high throughput and genome-wide ...
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 8

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Embedded Multi-Core Systems for Mixed Criticality Applications in Dynamic and Changeable Real-Time Environments (EMC2)

Start date: Apr 1, 2014, End date: Jun 30, 2017,

...lications in dynamic and changeable real-time environments.The EMC2 project focuses on the industrialization of European research outcomes and builds on the results of previous ARTEMIS, European and National projects. It provides the paradigm shift to a new and sustainable system architecture which is suitable to handle open dynamic systems.EMC² is part of the European Embedded Systems industry st ...
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 101

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Vaccination against Shigella and ETEC: novel antigens, novel approaches (STOPENTERICS)

Start date: Nov 1, 2010, End date: Apr 30, 2017,

To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunity (ii) to improve the immunogenicity of Shigella glycoconjugates by using synthetic oligosacharides mimicking the lipopolysa ...
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 20

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Integrated Approaches to Food Allergen and Allergy Risk Management (IFAAM)

Start date: Mar 1, 2013, End date: Feb 28, 2017,

Up to 20 million European citizens suffer from food allergy. However management of both food allergy (by patients and health practitioners) and allergens (by industry) is thwarted by lack of evidence to either prevent food allergy developing or protect adequately those who are already allergic. iFAAM will develop evidence-based approaches and tools for MANAGEMENT of ALLERGENS in FOOD and integrate ...
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 46

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Integrating Post-Abortion Family Planning Services into China's existing abortion service in hospital settings (INPAC)

Start date: Aug 1, 2012, End date: Jan 31, 2017,

In 2008 an estimated 13 million induced abortions were conducted in China. Induced abortions are associated with a high risk of injury or long-term physical and psychological morbidity and a heavy social and economic burden. Most abortions occur in cities and the epidemic affects young and unmarried women as well as rural-to-urban migrant women.The large number of abortions is primarily due to con ...
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 7

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European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke (EuroHYP-1)

Start date: Feb 1, 2012, End date: Jan 31, 2017,

The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
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 38

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African Vector Control: New Tools (AvecNet)

Start date: Feb 1, 2011, End date: Dec 31, 2016,

...ol and elimination. Our carefully balanced, multidisciplinary team of European and African experts includes vector biologists, engineers, epidemiologists, social scientists and leaders of large supranational consortia. These partners are all prominent members of global vector control research programs having unique specialization in Africa-centric projects.Together we have developed a proposal f ...
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 17

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PRIMES: Protein interaction machines in oncogenic EGF receptor signalling (PRIMES)

Start date: Dec 1, 2011, End date: Nov 30, 2016,

"PRIMES focuses on the role of protein interactions to assemble dynamic molecular machines that receive and process information to coordinate cellular responses. PRIMES investigates the following: (i) How do protein interactions contribute to the generation of biological specificity in signalling? (ii) How do pathogenetic perturbations affect protein interaction networks? (iii) How can we exploit ...
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 14

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The Human Brain Project (HBP)

Start date: Oct 1, 2013, End date: Sep 30, 2016,

... for collaboration that links the partners under strong scientific leadership and professional project management, providing a coherent European approach and ensuring effective alignment of regional, national and European research and programmes. The project work plan is organized in the form of thirteen subprojects, each dedicated to a specific area of activity.A significant part of the budget wi ...
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 116

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Kinetoplastid Drug Development: strengthening the preclinical pipeline (KINDRED)

Start date: Sep 1, 2013, End date: Aug 31, 2016,

The trypanosomatid diseases, leishmaniasis, Human African trypanosomiasis (HAT) and Chagas disease (CD), continue to impart a heavy toll on human health. The treatments available are limited and threatened by drug resistance with few newdrugs in the pipeline. The KINDReD consortium integrates five leading academic laboratories in Europe (Portugal, United Kingdom, and Switzerland), the USA (Califor ...
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 14

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Systems biology of liver cancer: an integrative genomic-epigenomic approach (MODHEP)

Start date: Jan 1, 2011, End date: Jun 30, 2016,

"Cancer is a complex disease involving multiple genetic and epigenetic events occurring, and influencing each other, over a long period of time. Understanding cancer, and ultimately developing effective targeted therapies, will therefore require that mutations and epigenetic alterations be systematically investigated during the multiple stages of disease development, from identifiable pre-neoplast ...
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 18

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Application of new technologies and methods in nutrition research – the example of phenotypic flexibility (NutriTech)

Start date: Jan 1, 2012, End date: Jun 30, 2016,

NutriTech will build on the foundations of traditional human nutrition research using cutting-edge analytical technologies and methods to comprehensively evaluate the diet-health relationship and critically assess their usefulness for the future of nutrition research and human well-being. Technologies include genomics, transcriptomics, proteomics, metabolomics, laser scanning cytometry, NMR based ...
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 25

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Prospective cohort study of residents near the Semipalatinsk nuclear test site - feasibility (SEMI-NUC)

Start date: Apr 1, 2013, End date: Mar 31, 2016,

...pulations residing around the Semipalatinsk nuclear test site and/or who have been extensively involved in the low dose risk research. The group will include European and international scientists with expertise in epidemiology, dosimetry, radiation biology and clinical medicine. At the end of the project, a detailed report based on the results of the work conducted will be developed, critically re ...
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 8

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Electronic Health Record systems for Clinical Research (EHR4CR)

Start date: Mar 1, 2011, End date: Feb 29, 2016,

Current medical needs, the growth of targeted therapies and personalized medicines, and escalating R&D costs result in formidable cost pressures on healthcare systems and the pharmaceutical industry. Clinical research is also growing in complexity, labour intensity and cost. There is a growing realization that the development and integration of Electronic Health Record systems (EHRs) for medical ...
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 37

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European Research Training in the Ubiquitin Proteasome System (UPStream)

Start date: Nov 1, 2011, End date: Oct 31, 2015,

The main objective of the international training network UPStream is the training of a novel generation of European scientist in a critical and complex field of modern biology: the understanding of the regulation of the UPS and its potential use for drug development. The importance of this process is illustrated by the imperious necessity to destroy certain proteins during several phases of the ce ...
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 10

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Dissecting the Immunological Interplay between Poverty Related Diseases and Helminth Infections: An African-European Research Initiative (IDEA)

Start date: Mar 1, 2010, End date: Aug 31, 2015,

Worm infections are receiving increased attention due to: the wide geographic overlap in occurrence between worms and HIV, TB and malaria; the large proportion of individuals (minimal estimates around 25%) co-infected with worms and HIV/TB/ malaria; the potential risk of increasing disease burden; the very limited understanding of the impact by worm infections on HIV-, TB- and malaria-specific imm ...
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 23

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Open Collaborative Model for Tuberculosis Lead Optimisation (ORCHID)

Start date: Jan 1, 2011, End date: Jun 30, 2015,

"Early stage Drug Discovery efforts over the last 5 years have resulted in the identification of a number of promising lead compounds in the fight against TB. These leads need to be further progressed and optimised into candidates for pre-clinical development through the Drug Development progression cascade.Three compound families are of particular interest: 1) InhA Inhibitors, 2) New potent whole ...
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 14

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Overcoming clinical relapse in multiple myeloma by understanding and targeting the molecular causes of drug resistance (OVER-MYR)

Start date: Jan 1, 2012, End date: Jun 30, 2015,

...subpopulations of MMCii) drugs induce alterations in cells of the ‘niche’ that promote drug-resistance.OVER-MYR integrates a network of outstanding researchers from 6 EU countries with internationally recognized experience in clinics and human and animal models of MM, who will jointly:WP1: Study the molecular alterations in primary MM and environment cells in samples obtained from a large number o ...
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 11

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Semantic Interoperability for Health Network (SemanticHealthNet)

Start date: Dec 1, 2011, End date: May 31, 2015,

...ive, will inform the shape of the Virtual Organisation that this Network will establish to sustain semantic interoperability developments and their adoption.The consortium comprises more than 40 internationally recognised experts, including from USA and Canada, ensuring a global impact.
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 18

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Health, environmental change and adaptive capacity: mapping, examining and anticipating future risks of water-related vector-borne diseases in eastern Africa (HEALTHY FUTURES)

Start date: Jan 1, 2011, End date: Dec 31, 2014,

The HEALTHY FUTURES project is motivated by concern for the health impacts of environmental changes. HEATHLY FUTURES aims to respond to this concern through construction of a disease risk mapping system for three water-related high-impact VBDs (malaria, Rift valley fever and schistosomiasis) in Africa, accounting for environmental/climatic trends and changes in socio-economic conditions to predic ...
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 17

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Environmental and Economic BEnefits from BIochar clusterS in the Central area (E2BEBIS)

Start date: May 31, 2012, End date: Nov 29, 2014,

....The E2BEBIS project aims at developing regional energy clusters adopting the biochar technology, and at advancing the related policies through its full legal adoption by competent authorities at the national and the EU level. The transnational Central dimension helps considering the adoption of such technology in context featuring different environmental conditions, different types of biomass, di ...
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 8

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Health Education and Community Integration: Evidence based Strategies to increase equity, integration and effectiveness of reproductive health services for poor communities in Sub Saharan Africa (INTHEC)

Start date: Mar 1, 2010, End date: Aug 31, 2014,

Objectives: The research aims to improve the delivery of reproductive health (RH) services in Tanzania and Niger by generating new evidence about effective ways to strengthen the provision, uptake, equity and effectiveness of adolescent reproductive health (ARH) programmes. Background: Poor adolescent reproductive health (ARH) continues to be a major cause of morbidity and worsening poverty for th ...
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 8

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The targeted development of a new generation Vaccine for Schistosomiasis (TheSchistoVac)

Start date: Feb 1, 2010, End date: Jul 31, 2014,

The aim of this project is to develop a new generation vaccine for schistosomiasis. The vaccine will be based on exposed proteins and/or glycans of the vulnerable skin stage schistosomula, making it safe and effective. The life stage-specific vaccine target selection strategy is based on state-of-the-art schistosomal transcriptomics and glycomics technologies and data, and unique serum and sample ...
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 14

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PLANT food supplements: Levels of Intake, Benefit and Risk Assessment (PlantLIBRA)

Start date: Jun 1, 2010, End date: May 31, 2014,

...information and better tools (e.g., metadatabanks). PlantLIBRA is structured to develop, validate and disseminate data and methodologies for risk and benefit assessment and implement sustainable international cooperation. International cooperation, on-spot and in-language capacity building are necessary to ensure the quality of the plants imported in the EU. PlantLibra spans 4 continents and 23 pa ...
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