4 European Projects Found
Searched on 125080 European Projects
FINISHED
Developing and Testing a novel, low-cost, effective HOOKworm VACcine to Control Human Hookworm Infection in endemic countries (HOOKVAC)
Start date: Oct 1, 2013, End date: Sep 30, 2017,
...d by hookworm, primarily in sub-Saharan Africa, Southeast Asia, and Latin America. Hookworm infection ranks number one in terms of Years Lost from Disability from a neglected infectious disease, and among the top 3 in terms of lost Disability-Adjusted Life Years. HOOKVAC will be developing the first and only vaccine for human hookworm infection. A bivalent, low-cost vaccine candidate will be cli ...
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9
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Biomaterials for Tracheal Replacement in Age-related Cancer via a Humanly Engineered Airway (BIOtrachea)
Start date: Apr 1, 2012, End date: Mar 31, 2017,
Age-related cancers, especially of the trachea, are neoplastic lesions that significantly impact upon the lives of thousands of European patients each year. Unfortunately, most present with inoperable lesions for which median survival is less than 12 months. Based on our previous clinically successful experiences with in vivo completely tissue engineered tracheal replacement in benign tracheal dis ...
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13
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Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)
Start date: Mar 1, 2012, End date: Feb 28, 2017,
The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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32
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Development and evaluation of a quantitative imaging technique for assessment of nanoparticle drug delivery across the blood-brain barrier: Applications for brain cancer therapeutics (OncoNanoBBB)
Start date: Jan 1, 2012, End date: Dec 31, 2015,
...at transiently and reversibly opens the BBB to entry of compounds into the brain without inducing tissue injury. It is based on patented lipid-like structures and has been shown to deliver both small molecules and large proteins effectively into the brain. The lead delivery compound for brain cancer appears to be safe and well tolerated on the basis of pre-clinical testing. We initially seek to de ...
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