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"RNA molecules have been already proven to be a key target for disease therapy as well as a tool for the development of new drugs. Since the discovery of small non coding RNA (ncRNA) and all the associated phenomena like RNA interference, the possibility of using RNA-based drugs has become a subject of great interest in the pharmaceutical and clinical fields. ncRNA is at the core of many cellular ...

There is growing evidence that molecules classically allocated to nervous system function, such as the neurotrophic factors, are produced by lymphocytes and can also regulate their function. The neurotrophic family includes the GDNF ligands (GFLs), which signal through the RET tyrosine kinase receptor. In humans, mutations of the proto-oncogene Ret have been linked to different diseases, such as c ...