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"ESNATS aims at developing a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs). ESNATS will address current drug-testing shortcomings: - testing takes place late in the development cycle - animal test systems bear the risk of non-prediction due to ...

The rapid increase of life expectancy in Europe is essentially a positive outcome from improved health care and socioeconomic progress. However age-related deteriorations of health greatly impinge upon the health care and social security systems. This fosters an increasing necessity of keeping as long as possible the elderly in relatively healthy conditions. Unravelling the fundamental mechanisms ...