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5 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Circulating Tumor Cells TheRapeutic APheresis: a novel biotechnology enabling personalized therapy for all cancer patients (CTCtrap)

Start date: Sep 1, 2012, End date: Aug 31, 2016,

"Chemotherapy is slowly being supplemented by a new generation of drugs that recognize specific targets in or on cancer cells and has proven to be more effective with markedly fewer side effects. During the course of the disease alternative oncogenic signaling pathways take over inevitably leading to drug resistance. As a consequence renewed tumor analysis is required to redefine the optimal treat ...
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Studying Resistance to Cancer Therapeutics in Prostate Cancer (RESICT-PC)

Start date: May 1, 2014, End date: Apr 30, 2016,

Several new therapies have been recently approved for the treatment of castration-resistant prostate cancer (CRPC) but drug resistance invariably develops and eventually causes death. Currently, the knowledge on the molecular mechanisms underlying resistance is limited; this is an area of urgent unmet medical need to allow improved treatments for patients. This study proposes a multidisciplinary e ...
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CHD1 Deletion: Implications to Outcome and Treatment in Prostate Cancer (CDELP)

Start date: Apr 4, 2014, End date: Apr 3, 2016,

Prostate cancer can be stratified as ETS gene rearranged (ETSR) andnon-rearranged (ETSNR), with the latter comprising a heterogeneousgroup of 50-60% of all cancers. This project will characterize a subgroupof ETSNR cancers that have a CHD1 deletion (CHD1del). Recentsequencing studies have elucidated CHD1- cancers as ETSNR, andcommonly PTEN and p53 wildtype and SPOP mutated, comprising up to26% of ...
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Systems Biology of Colorectal Cancer (SYSCOL)

Start date: Jan 1, 2011, End date: Dec 31, 2015,

Colorectal cancer (CRC) is one of the most common cancers in both males and females, and it is perhaps the best understood of all epithelial tumors in terms of its molecular origin. Yet, despite large amount of work that has concentrated on understanding of colon tumorigenesis, we still do not know the full complement of molecular lesions that are individually necessary – and together sufficient – ...
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Safety and Appropriateness of Growth hormone treatments in Europe (SAGhE)

Start date: Jun 1, 2009, End date: Nov 30, 2012,

Recombinant growth hormone (GH) has been used since 1985. Current indications for GH use in children include GH deficiency and an increasing number of conditions where childhood short stature is not primarily due to deficient GH secretion. Approximately 40 000 children in the EU are treated with daily injections of GH. The efficacy of GH to increase adult height is undisputed in children with seve ...
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