Search for European Projects

Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Early-life stressors and LifeCycle health (LIFECYCLE)

Start date: Jan 1, 2017, End date: Dec 31, 2021,

Early life is an important window of opportunity to improve health across the full lifecycle. European pregnancy and child cohort studies together offer an unique opportunity to identify a wide range of early life stressors linked with individual biological, developmental and health trajectory variations, and to the onset and evolution of non-communicable diseases. LIFECYCLE will establish the Eur ...
Read Project

 19

 FINISHED 

Reaching the effects of gastric bypass on diabetes and obesity without surgery (BYPASSWITHOUTSURGERY)

Start date: Jan 1, 2017, End date: Dec 31, 2021,

Gastric bypass surgery results in massive weight loss and diabetes remission. The effect is superior to intensive medical treatment, showing that there are mechanisms within the body that can cure diabetes and obesity. Revealing the nature of these mechanisms could lead to new, cost-efficient, similarly effective, non-invasive treatments of these conditions. The hypothesis is that hyper-secretion ...
Read Project

 2

 FINISHED 

Mechanism of DNA-protein cross-link repair in S phase (DPC_REPAIR)

Start date: Jan 1, 2017, End date: Dec 31, 2021,

DNA-protein cross-links (DPCs) are common DNA lesions caused by endogenous, environmental, and chemotherapeutic agents. Cells are susceptible to these lesions during S phase, as DPCs impede replication fork progression and are likely to induce genomic instability, a cause of cancer and aging. Despite its relevance to human health, the repair of DPCs is poorly understood. Research on DPC repair has ...
Read Project

 1

 FINISHED 

An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century (EU-ToxRisk)

Start date: Jan 1, 2016, End date: Dec 31, 2021,

The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
Read Project

 43

 FINISHED 

GALAXY: Gut-and-liver axis in alcoholic liver fibrosis (GALAXY)

Start date: Jan 1, 2016, End date: Dec 31, 2021,

Alcohol overuse is an important societal challenge with annual healthcare costs of over €22 billion in Europe. Alcohol is the main cause of liver cirrhosis, which is the 5th and 7th most common cause of life years lost in respectively Eastern and Western Europe. Cirrhosis is considered irreversible but its precursor, liver fibrosis, is reversible when detected before disease progression. GALAXY pr ...
Read Project

 12

 FINISHED 

The makeup of the modern horse: a history of the biological changes introduced by human management (PEGASUS)

Start date: Dec 1, 2016, End date: Nov 30, 2021,

The horse provided us with rapid transportation, an almost unrivaled secondary product that tremendously impacted the politico-economical trajectory of our societies, revolutionizing the circulation of ideas, people, languages, religions and communication. Horse chariotry and cavalry also changed warfare and beyond the battlefield new equestrian technologies have stimulated agricultural productivi ...
Read Project

 2

 FINISHED 

From Fermi to Planck : a bottom up approach (NuBSM)

Start date: Oct 1, 2016, End date: Sep 30, 2021,

The Standard Model of particle physics is a hugely successful theory that has been tested in experiments at ever increasing energies, culminating in the recent discovery of the Higgs boson. Nevertheless, some major riddles cannot be addressed by the Standard Model, such as neutrino oscillations, the existence of Dark Matter, the absence of antimatter in the Universe. New fundamental principles, in ...
Read Project

 3

 FINISHED 

Matrix during cancer progression (MATRICAN)

Start date: Sep 1, 2016, End date: Aug 31, 2021,

The extracellular matrix (ECM) is known to play a critical role in driving cancer progression, and yet we lack knowledge of its composition and structure. The goal of my ERC project is to investigate how alterations in biochemical composition and structural properties of the ECM during cancer progression impact on cell behaviour to drive metastasis, which is responsible for over 90% of cancer pati ...
Read Project

 1

 FINISHED 

Northern Europe's timber resource - chronology, origin and exploitation (TIMBER)

Start date: Sep 1, 2016, End date: Aug 31, 2021,

Empirical evidence for the history of the exploitation of the timber resource in Northern Europe is stored in the material record. Archaeological finds, art-historical objects and built heritage have provided us with an extensive dataset of precisely dated wood from heritage contexts. This material is the key to details about the usage, condition and availability of the timber resource and details ...
Read Project

 1

 FINISHED 

Foetal Intestinal Stem Cells in Biology and Health (StemHealth)

Start date: Aug 1, 2016, End date: Jul 31, 2021,

There is currently no medical cure for the millions of individuals affected by inflammatory bowel disease (IBD). These patients suffer from bleeding along the gastrointestinal tract due to epithelial ulceration, which causes severe abdominal pain, diarrhoea and malnutrition. This is due to the severely compromised integrity of the intestinal epithelium. I propose that patients with IBD will benefi ...
Read Project

 1

 FINISHED 

Dissecting the constraints that define the eukaryotic DNA replication program (REPLICONSTRAINTS)

Start date: Aug 1, 2016, End date: Jul 31, 2021,

DNA replication is essential for the perpetuation of life and, yet, it is also a major source of genomic instability that can lead to cancer and other human diseases. Despite the vast efforts invested in establishing the origins of genomic instability, the mechanisms that coordinate faithful genome duplication while ensuring its integrity remain unknown.This dilemma is molecularly best exemplified ...
Read Project

 1

 FINISHED 

Mumps VIRus EXploitation of the human adhesion receptor GPR125 (VIREX)

Start date: Jul 1, 2016, End date: Jun 30, 2021,

Mumps virus is a re-emerging pathogen that causes painful inflammatory symptoms, such as parotitis (salivary gland infection) and orchitis (testis infection). It is highly neurotropic with evidence of brain infection in half of cases and clinical evidence in up to 10%. It is a small RNA virus belonging to the family of paramyxoviridae that includes e.g. viruses for measles and pneumonia, all havin ...
Read Project

 1

 FINISHED 

Policy, practice and patient experience in the age of intensified data sourcing (POLICYAID)

Start date: Jun 1, 2016, End date: May 31, 2021,

The European healthcare services have begun collecting tissue samples and healthcare data from patients on an unprecedented scale. With POLICYAID we suggest the term 'intensified data sourcing' to describe these attempts at getting more data, on more people, of better quality while simultaneously making the data available for multiple uses. Data are used for research, for financial remuneration pu ...
Read Project

 1

 FINISHED 

Chromosomal Common Fragile Sites: Unravelling their biological functions and the basis of their instability (CFS modelling)

Start date: May 1, 2016, End date: Apr 30, 2021,

Cancer and other diseases are driven by genomic alterations initiated by DNA breaks. Within our genomes, some regions are particularly prone to breakage, and these are known as common fragile sites (CFSs). CFSs are present in every person and are frequently sites of oncogenic chromosomal rearrangements. Intriguingly, despite their fragility, many CFSs are well conserved through evolution, suggesti ...
Read Project

 1

 FINISHED 

Diplomatic Face-Work - between confidential negotiations and public display (DIPLOFACE)

Start date: Apr 1, 2016, End date: Mar 31, 2021,

The rise of social media, coupled with intensifying demands for more transparency and democracy in world politics, brings new challenges to international diplomacy. State leaders and diplomats continue to react to traditional media, but now also attempt to present themselves proactively through tweets, public diplomacy and nation branding. These efforts often take place simultaneously and sometime ...
Read Project

 2

 FINISHED 

Exploring and exploiting the potential of extinct genome sequencing (Extinction Genomics)

Start date: Apr 1, 2016, End date: Mar 31, 2021,

Palaeogenomics is the nascent discipline concerned with sequencing and analysis of genome-scale information from historic, ancient, and even extinct samples. While once inconceivable due to the challenges of DNA damage, contamination, and the technical limitations of PCR-based Sanger sequencing, following the dawn of the second-generation sequencing revolution, it has rapidly become a reality. Ind ...
Read Project

 1

 FINISHED 

The Genus Haslea, New marine resources for blue biotechnology and Aquaculture (GHaNA)

Start date: Mar 1, 2017, End date: Feb 28, 2021,

The GHaNA project aims to explore and characterize a new marine bioresource, for blue biotechnology applications in aquaculture, cosmetics and possibly food and health industry. The project will determine the biological and chemical diversity of Haslea diatoms to develop mass-scale production for viable industrial applications by maximising biomass production and associated high-value compound pro ...
Read Project

 11

 FINISHED 

Teaching Emerging Methods in Palaeoproteomics for the European Research Area (TEMPERA)

Start date: Mar 1, 2017, End date: Feb 28, 2021,

TEMPERA will provide international, intersectoral and interdisciplinary state-of-the-art doctoral training to prepare the next generation of specialists in mass spectrometry-based ancient protein residues analysis for biomolecular diagnostics and conservation of cultural heritage material.Due to their chemical and mechanical properties, proteins have always represented the category of biomolecules ...
Read Project

 6

 FINISHED 

Probing topology and dynamics in driven quantum many-body systems (TopDyn)

Start date: Feb 1, 2016, End date: Jan 31, 2021,

If the twentieth century was about discovering the basic laws of quantum mechanics, then the twenty first century will be about pushing them to new frontiers and learning how to control them. Condensed matter systems are predicted to host many intriguing and potentially useful quantum phenomena, though materials where they can be realized are rare. This motivates me to seek alternative routes for ...
Read Project

 1

 FINISHED 

Innovative Nanowire DEvicE Design (INDEED)

Start date: Feb 1, 2017, End date: Jan 31, 2021,

Nanowires (NWs) exhibit unique properties that make them potential building blocks for a variety of next generation NanoElectronics devices. Recent advances have shown that NWs with predefined properties can be grown, offering a new paradigm enabling functional device prototypes including: biosensors, solar cells, transistors, quantum light sources and lasers. The critical mass of scientific knowl ...
Read Project

 12

 FINISHED 

Optical Infrared Coordination Network for Astronomy (OPTICON)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europe’s nations ...
Read Project

 34

 FINISHED 

Towards enduring mouse resources and services advancing research into human health and disease (INFRAFRONTIER2020)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st ...
Read Project

 33

 FINISHED 

Quantum Information Access and Retrieval Theory (QUARTZ)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

Quantum Information Access and Retrieval TheoryWe aim to establish an European Training Network (ETN) on QUantum information Access and Retrieval Theory (QUARTZ). Towards a new approach to Information Access and Retrieval (IAR) addressing the challenges of the dynamic and multimodal nature of the data and user interaction context, QUARTZ aims to educate its Early Stage Researchers (ESRs) to adopt ...
Read Project

 7

 FINISHED 

Hybrid Optomechanical Technologies (HOT)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The hybrid optomechanical technologies (HOT) consortium will lay the foundation for a new generation of devices, which connect, or indeed contain, several platforms at the nanoscale in a single “hybrid” system. As hybrid interfaces they will allow to harness the unique advantages of each subsystem within a nano-scale footprint, while as integrated hybrid devices they will enable entirely novel fun ...
Read Project

 17

 FINISHED 

European training Network for In situ imaGing of dynaMic processes in heterogeneous subsurfAce environments (ENIGMA)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

The ENIGMA network will train a new generation of young researchers in the development of innovative sensors, field survey techniques and inverse modelling approaches. This will enhance our ability to understand and monitor dynamic subsurface processes that are key to the protection and sustainable use of water resources. ENIGMA focuses mainly on critical zone observation, but the anticipated tech ...
Read Project

 11

 FINISHED 

Small vessel diseases in a mechanistic perspective: Targets for InterventionAffected pathways and mechanistic exploitation for prevention of stroke and dementia (SVDs-at-target)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Stroke and dementia rank among the most pressing health issues in Europe. Cerebral small vessel diseases (SVDs) have emerged as a central link between these two major co-morbidities. SVDs account for more than 30% of strokes and at least 40% of dementia cases. They encounter multiple distinct diseases that can be separated based on their underlying genetic defects, risk factors, and clinical prese ...
Read Project

 14

 FINISHED 

European Academy for Biomedical Science (ENABLE)

Start date: Jul 1, 2016, End date: Dec 31, 2020,

The proposed European Academy for Biomedical Science (ENABLE) consortium will connect aspiring European researchers of tomorrow with prominent scientists of today, in particular to inspire and to give them the necessary tools to follow in their footsteps. ENABLE will organize peer-reviewed symposia celebrating European life science achievements from molecule to man/patient. These symposia will hav ...
Read Project

 6

 FINISHED 

INtestinal Tissue ENgineering Solution (INTENS)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Short Bowel Syndrome (SBS) is a condition that occurs when part or the entire small intestine is missing or has been removed during surgery. This condition renders the bowel incapable of fulfilling its nutritional function (intestinal failure). There is no cure for SBS. Parenteral (intravenous) nutrition (PN) and bowel transplantation are currently the preferred options for nutrition in children a ...
Read Project

 9

 FINISHED 

Natural Toxins and Drinking Water Quality - From Source to Tap (NaToxAq)

Start date: Jan 1, 2017, End date: Dec 31, 2020,

Clean drinking water is crucial to human health and wellbeing. The ambition of the NaToxAq ETN network is to expand the research basis for EU’s leading role in securing high quality drinking waters for its citizens. Focus is on natural toxins – a large group of emerging contaminants with unknown impact on drinking water resources. Both known toxins, like cyanotoxins, cyanogenic glucosides and terp ...
Read Project

 10

 FINISHED 

Integrated inter-sector framework to increase the thermal resilience of European workers in the context of global warming (HEAT-SHIELD)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Environmental heating is a growing challenge for our community and problems are already experienced by millions of Europeans during the summertime and aggravated during heat waves or occupational settings. In addition to the well-known health risks related to severe heat stress, a number of studies have confirmed significant loss of productivity due to hyperthermia. Even if countries adopt the EU ...
Read Project

 21

 FINISHED 

State Formation Through the Local Production of Property and Citizenship (Local State)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

The key concern of the proposed research is how political power is established and reproduced through the production of the fundamental social contracts of property and citizenship. We will re-define the research on so-called failed and weak states, by examining what political authority is actually exercised rather than measuring how they fall short of theoretical ideals. In developing countries w ...
Read Project

 1

 FINISHED 

“In Vivo Click PET Imaging Agents”: Improving clinical companion diagnostics (Click-It)

Start date: Jan 1, 2016, End date: Dec 31, 2020,

Companion diagnostics are crucial for drug development and disease management with regard to patient selection, therapy planning and monitoring. Nanomedicines such as antibodies have been proven to be optimal disease-targeting agents because they generally exhibit superior target uptake and retention. However, to date, nuclear imaging of nanomedicines has been limited to the use of long-lived isot ...
Read Project

 6

 FINISHED 

Scalable Quantum Photonic Networks (SCALE)

Start date: Dec 1, 2015, End date: Nov 30, 2020,

It is an outstanding challenge in quantum physics of today to scale small proof-of-concept experimental demonstrations into larger quantum networks. In the last decade, solid-state photonic systems have matured significantly, and an ambitious research project on such scaling seems viable. With the present proposal we intend to take up this challenge and exploit single quantum dots in photonic-crys ...
Read Project

 1

 FINISHED 

Doctoral Industrial School for Vaccine Design through Structural Mass Spectrometry (VADEMA)

Start date: Nov 1, 2016, End date: Oct 31, 2020,

Vaccines discovered from empirical approaches and consisting in killed, live-attenuated microorganisms or purified components have led to the successful control of many devastating diseases. Several novel technologies, such as recombinant DNA technology, glycoconjugation, reverse vaccinology have opened the possibility of designing vaccines previously considered impossible to make. Despite decades ...
Read Project

 2

 FINISHED 

Smart capture phases for proteomics, glycomics and biomarker assays (BioCapture)

Start date: Nov 1, 2016, End date: Oct 31, 2020,

The overall objective of BioCapture is to develop novel robust assays for proteinaceous biomarkers associated with cancer and to develop innovative tools for assaying elusive cancer related posttranslational modifications in proteins. This will be achieved by exploiting robust glycan, peptide and protein binders in the form of Molecularly Imprinted Polymers (MIPs) or plastic antibodies alongside g ...
Read Project

 8

 FINISHED 

Systematic Decoding of Deubiquitylase-Regulated Signaling Networks (DUB-DECODE)

Start date: Oct 1, 2015, End date: Sep 30, 2020,

Cellular processes are largely governed by sophisticated protein posttranslational modification (PTM)-dependent signaling networks, and a systematic understanding of regulatory PTM-based networks is a key goal in modern biology. Ubiquitin is a small, evolutionarily conserved signaling protein that acts as a PTM after being covalently conjugated to other proteins. Reversible ubiquitylation forms th ...
Read Project

 1

 FINISHED 

OMT - Optomechanical Technologies (OMT)

Start date: Oct 1, 2016, End date: Sep 30, 2020,

The proposed project is built on the successful training and research experience of the leading European research groups working in the field of cavity optomechanics. Our ENT unites a total of 14 leading groups in the field, of which two are major industrial players that utilize MEMS and NEMS - Bosch and IBM. The main goal of the project is to exploit optomechanical interactions in views of novel ...
Read Project

 14

 FINISHED 

Trust, Global Traders, and Commodities in a Chinese International City (TRODITIES)

Start date: Oct 1, 2015, End date: Sep 30, 2020,

Trust, Global Traders, and Commodities in a Chinese International CityYiwu, a city of 2 million in China’s commercially vibrant Zheijang province, is known by traders from countries including Afghanistan and Syria, the Ukraine and Mexico, and the UK and Russia, as being the world’s hub for wholesale of ‘small commodities’. Journalists have recently been struck both by Yiwu’s significance to consu ...
Read Project

 4

 FINISHED 

Techniques and Technologies for Effective Wood Procurement (TECH4EFFECT)

Start date: Oct 1, 2016, End date: Sep 30, 2020,

The project focuses on increasing access to wood resources through more efficient silviculture and a better understanding of the business models governing the procurement of forest operations services. The project further considers increasing efficiency in forest harvesting and collection, and the reduction of soil impact from forest operations, and puts forward ways of making this a measurable an ...
Read Project

 19

 FINISHED 

Connecting the Extreme (ConTExt)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

Advances in technology and methodology over the last decade, have enabled the study of galaxies to the highest redshifts. This has revolutionized our understanding of the origin and evolution of galaxies. I have played a central role in this revolution, by discovering that at z=2, when the universe was only 3 Gyr old, half of the most massive galaxies were extremely compact and had already complet ...
Read Project

 1