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Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

ANAEROBIC POLLUTANT DEGRADATION WITH OXYGEN (POLLOX)

Start date: May 1, 2014, End date: Apr 30, 2019,

"Contamination with organic pollutants is widespread in nature and a notorious threat to our water resources. Two central paradigms are currently understood to control biodegradation in groundwater and sediments: (i) Redox gradients and interphases between compartments are hot-spots for contaminant breakdown, and (ii) biodegradation is primarily limited by local electron acceptor availability, in ...
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Identifying and Overcoming Bottlenecks of Micropollutant Degradation at Low Concentrations (MicroDegrade)

Start date: May 1, 2014, End date: Apr 30, 2019,

"MicroDegrade aims to reveal bottlenecks of degradation, and to identify superior bioremediation strategies for a most notorious environmental pollution of our time: chemical micropollutants at low (sub-ug/L) concentrations. Finding out why micropollutants occur in ground and surface water despite the presence of bacterial degraders has become an elusive goal for microbiologists, environmental sci ...
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Chromatin states in neurogenesis – from understanding chromatin loops to eliciting neurogenesis for repair (ChroNeuroRepair)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

The mechanisms regulating neural stem cells and their progression to neurogenesis are important not only to understand brain development and evolution, but also to elicit neurogenesis after brain injury. Our recent findings imply novel chromatin-associated proteins in the regulation of neural stem cell fate and neurogenesis. Therefore this project aims to understand the molecular mechanisms of how ...
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 1

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Nuclear foundations of cellular potency (NUCLEARPOTENCY)

Start date: Feb 1, 2012, End date: Jan 31, 2018,

A fundamental question in biology is to understand the mechanisms underlying cell plasticity. Such plasticity or potency is essential to form multiple cell types upon differentiation. In mammals, upon fertilization and fusion of the gametes –two highly differentiated cells- intense chromatin remodeling and epigenetic reprogramming, the reversion into an undifferentiated state, are essential to res ...
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Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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 19

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Upscaling human insulin-producing beta cell production by efficient differentiation and expansion of endoderm progenitors (HumEn)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

Despite progress in producing beta cells from human pluripotent stem cells (hPSCs) in recent years, full differentiation cannot be obtained in vitro. The HumEn project hypothesises that a fundamental understanding of the coupling between endodermal progenitor expansion and differentiation is relevant for elucidating how to a) generate glucose-responsive beta cells from hPSCs in vitro, and b) gener ...
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 9

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Methods for Integrated analysis of Multiple Omics datasets (MIMOmics)

Start date: Oct 1, 2012, End date: Sep 30, 2017,

MIMOmics develops statistical methods for the integrated analysis of metabolomics, proteomics, glycomics and genomic datasets in large studies. Our project is based on our involvement in studies participating in EU funded projects, i.e. GEHA, IDEAL, Mark-Age, ENGAGE and EuroSpan. In these consortia the primary goal is to identify molecular profiles that monitor and explain complex traits with nove ...
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 15

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Open Project for the European Radiation Research Area (OPERRA)

Start date: Jun 1, 2013, End date: May 31, 2017,

"Within the OPERRA project, it is proposed that the MELODI Association, as a well-advanced network, takes the lead in establishing the necessary structures able to manage the long-term European research programmes in radiation protection, also taking advantage of the valuable experience gathered through the DoReMi network of excellence. Whilst in fields adjacent to low-dose risk research (radioeco ...
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 71

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Risk, Stem Cells and Tissue Kinetics – Ionising Radiation (RISK - IR)

Start date: Nov 1, 2012, End date: Apr 30, 2017,

The magnitude of cancer risk in humans exposed to low radiation doses (
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 16

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Optical Imaging and Laser TEchniques for BIomedical Applications (OILTEBIA)

Start date: Apr 1, 2013, End date: Mar 31, 2017,

"OILTEBIA (Optical Imaging and Laser TEchniques for BIomedical Applications) is an Initial Training Network (ITN) that seeks to train researchers in a multidisciplinary environment where pulsed laser technology, sensor and signal processing techniques meet in the biomedicalenvironment to achieve novel optical imaging technologies from bench to bedside, spanning from basic research and drug discove ...
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 10

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BBMRI - Large Prospective Cohorts (BBMRI-LPC)

Start date: Feb 1, 2013, End date: Jan 31, 2017,

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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 36

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Taking Nanotechnological Remediation Processes from Lab Scale to End User Applications for the Restoration of a Clean Environment (NANOREM)

Start date: Feb 1, 2013, End date: Jan 31, 2017,

NANOREM is designed to unlock the potential of nanoremediation and so support both the appropriate use of nanotechnology in restoring land and aquifer resources and the development of the knowledge-based economy at a world leading level for the benefit of a wide range of users in the EU environmental sector.NANOREM uniquely takes a holistic approach to examining how the potential for nanoremediati ...
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 30

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Integrated Biotechnological Solutions for Combating Marine Oil Spills (Kill●Spill)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

Kill●Spill delivers innovative (bio)technologies, which can be integrated to the real sequences of state-of-the-art actions used currently to cleanup oil spills. The catalogue of Kill●Spill products & technologies is based on a review of technology & knowledge gaps in approaches of oil spill disasters and brings appropriate tools for 1st response, follow-up, and longer-term actions, specifically t ...
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 35

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Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation (INFRAFRONTIER-I3)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:• Develop a series of mutant alleles for every gene in the mouse genome• Determine the phenotypic consequences of each mutation• Identify mouse models for the complete dise ...
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 24

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The role of epithelial sodium channels in adult neural stem cells (ENAC_IN_ANSCS)

Start date: Jun 1, 2014, End date: May 31, 2016,

During adulthood, new neurons are generated by so called adult neurogenesis in the subgranular zone (SGZ) of the hippocampus and in the subventricular zone (SVZ) of the lateral ventricles. In these neurogenic niches, the adult neural stem cells (aNSCs) generate new neurons that are critical for establishing factual memories and mood control. Regulation of aNSCs is critical for cognitive brain func ...
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Proton Ionization Molecular Mass Spectrometry (PIMMS)

Start date: Jun 1, 2012, End date: May 31, 2016,

"The need for quantitative and fast identification of trace gaseous compounds in complex chemical matrices continuously pushes the limits of analytical chemistry in many areas of relevance to the EU, including food, health, the environment, and security. A relatively new broad-based and rapidly growing analytical technique, proton transfer reaction mass spectrometry (PTR-MS), combines excellent c ...
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 12

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Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE)

Start date: Oct 1, 2011, End date: Mar 31, 2016,

Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role in the drive towards personalised medicine remains uncertain.Based on harmonised and standardised European population cohorts we have built significant research collabo ...
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 31

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Realizing the European Network in Biodosimetry (RENEB)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

Creating a sustainable network in biological dosimetry that involves a large number of experienced laboratories throughout the EU will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperated action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently neede ...
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 28

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European Plant Phenotyping Network (EPPN)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The ability to quantitatively analyze plant phenotypic traits (from single cells to plant and stand level) and their dynamic responses to the environment is an essential requirement for genetic and physiological research, and the cornerstone for enabling applications of scientific findings to bioeconomy. Whereas molecular profiling technologies allow today the generation of a large amount of data ...
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 14

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Building data bridges between biological and medical infrastructures in Europe (BIOMEDBRIDGES)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The ESFRI infrastructures in Biological and BioMedical Sciences face substantial challenges in accessing and sharing data and resources. The BioMedBridges consortium brings together the six established ESFRI infrastructures with common goals to define, implement and deliver data interoperability across the biological and biomedical domains.The first objective is to ensure that interoperable stand ...
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 26

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Training for functional soil microorganism biodiversity (TRAINBIODIVERSE)

Start date: Jan 1, 2012, End date: Dec 31, 2015,

The TRAINBIODIVERSE ITN will provide professional skills and training for young scientists covering multi-disciplinary aspects of soil biodiversity, ecosystem services, their economic significance and practical implications and implementation.The researchers will gain access to European educational and network facilities and training aimed at ensuring the wellbeing of human populations and the con ...
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 11

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Systems Biology of Stem Cells and Reprogramming (SyBoSS)

Start date: Jun 1, 2010, End date: Nov 30, 2015,

Stem cells are central to emerging concepts in health, medicine and therapy. The realization that specific cell reservoirs retain multipotency for tissue establishment and replenishment has implications for both the emerging field of regenerative therapy and the long standing problems of cancer, ageing and degenerative diseases. Recently the prospects for regenerative therapy have been boosted by ...
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 11

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EUCOMM: Tools for Functional Annotation of the Mouse Genome (EUCOMMTOOLS)

Start date: Oct 1, 2010, End date: Sep 30, 2015,

The EUCOMMTOOLS Collaborative Project responds to the topic ‘HEALTH.2010.2.1.1-1: Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease.’ EUCOMMTOOLS will provide, in a systematic high-throughput way, genetic tools and resources contributing to the determination of every gene’s function in any cell type of the entire organism at any g ...
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 11

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Hybrid Fluorescence Optoacoustic Imaging (HIFI)

Start date: Sep 1, 2013, End date: Aug 31, 2015,

Optical imaging tools are in high demand by the biomedical research and clinical communities for applications that greatly impact the life sciences.The invention of fluorescent molecular tomography (FMT) a decade ago can be considered a breakthrough in optical imaging, as it allows for unprecedented, in-vivo, non-invasive and quantitative 3D imaging of fluorescent probes. However, it has been rec ...
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Trans-national Infrastructure for Plant Genomic Science (transPLANT)

Start date: Sep 1, 2011, End date: Aug 31, 2015,

Food and energy security are major challenges facing humanity in the coming decades. The falling costs of nucleotide sequencing are opening up significant opportunities for crop improvement through plant breeding and increased understanding of plant biology; in particular through interpreting the growing volume of plant genomics data in the context of phenotype. However, at present, there is no a ...
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 11

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Protein Binders for Characterisation of Human Proteome Function: Generation, Validation, Application (AFFINOMICS)

Start date: Apr 1, 2010, End date: Mar 31, 2015,

The Affinomics programme aims to leverage existing efforts in Europe to generate large-scale resources of validated protein-binding molecules (‘binders’) as affinity reagents for characterisation of the human proteome and to apply them in comprehensive structural and functional analyses of protein expression, interactions and complexes. Proteome targets will be focused on five categories of inter- ...
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 20

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Combining epidemiology and radiobiology to assess cancer risks in the breast, lung, thyroid and digestive tract after exposures to ionizing radiation with total doses in the order of 100 mSv or below (EpiRadBio)

Start date: Apr 1, 2011, End date: Mar 31, 2015,

Recent epidemiological studies suggest that cancer risk after exposures with doses comparable to the dose limits for occupationally exposed workers may be larger than assumed by ICRP in the derivation of these limits. The value of cancer risk from such exposures and its dependence on tissue, radiation type and individual factors is largely unknown. The innovative approach proposed here combines ep ...
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 23

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Cardiovascular Risk from Exposure to Low-dose and Low-dose-rate Ionizing Radiation (PROCARDIO)

Start date: Oct 1, 2011, End date: Mar 31, 2015,

Epidemiological evidence has established a link between cardiovascular disease and exposure of the heart and major vessels to doses above 500mGy. At lower doses the evidence for a detrimental effect is inconclusive. In part, this is due to the lack of appropriate epidemiological studies, coupled with lack of knowledge of the processes involved that is needed for construction of mathematical models ...
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 15

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Cognitive and Cerebrovascular Effects Induced by Low Dose Ionising Radiation (CEREBRAD)

Start date: Oct 1, 2011, End date: Mar 31, 2015,

The major elements of scientific uncertainty in the context of radiation protection policy and of risk assessment for cerebrovascular diseases, set the following key topics (1) the direct assessment of health effects through epidemiological studies of groups exposed to low doses, (2) doses-response and biological effects from different types of radiation and (3) the biological processes in cells a ...
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 12

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Epidemiological Studies of Exposed Southern Urals Populations (SOLO)

Start date: Mar 1, 2010, End date: Feb 28, 2015,

This project aims to improve estimates of the risks of long-term health effects associated with protracted external and internal radiation exposures, through further studies of exposed populations in the Southern Urals (Russian Federation). Specific objectives of the project are as follows: 1. To develop improved modules for estimating external doses to exposed cohorts in the Southern Urals. It is ...
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 13

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The study of Hsp90 through the use of nuclear magnetic resonance, small angle scattering and calorimetry (Hsp90NMR)

Start date: Feb 1, 2013, End date: Jan 31, 2015,

Proper protein folding is essential for cellular homeostasis. Cells employ a large array of chaperones to ensure protein adopt the proper conformation. Hsp90 is an important chaperone and comprises of 1-2% of all protein is eukaryotic cells. Additionally, Hsp90 is upregulated in cancerous cells to facilitate fast proliferation. There are several X-ray crystal structures available for Hsp90 free ...
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Support of Patient Empowerment by an intelligent self-management pathway for patients (EMPOWER)

Start date: Feb 1, 2012, End date: Jan 31, 2015,

Patient Empowerment involves patients to a greater extent in their own healthcare process and disease management becomes an integrated part of their daily life. The capability of self-management opens the possibility for patients not only to contribute to their own healthcare but also to be more in control of their disease. EMPOWER will develop a modular and standard-based Patient Empowerment Fram ...
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 7

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Coordinating the cooperation of the ESFRI project Infrafrontier with the International Phenotyping Consortium (IMPC) (INFRACOMP)

Start date: Oct 1, 2011, End date: Sep 30, 2014,

InfraCoMP will establish efficient coordination mechanisms between the ESFRI project Infrafrontier and the International Mouse Phenotyping Consortium. Infrafrontier is a pan-European initative to build a sustainable research infrastructure for systemic phenotyping, archiving and distribution of mouse models of human diseases. The IMPC is a global project to carry out systemic phenotyping of mouse ...
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 9

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Development of COMBInatorial BIOmarkers for subclinical atherosclerosis (COMBI-BIO)

Start date: Oct 1, 2012, End date: Sep 30, 2014,

"Systems biology involves the analysis of relationships among the elements in a system, viewed as an integrated and interacting network of genes, proteins and biochemical reactions. We have pioneered the use of metabolic profiling and the metabolome-wide association study (MWAS) approach, involving high-throughput spectroscopic screening, to capture comprehensive data on a range of exposures affec ...
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 6

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Transport related Air Pollution and Health impacts – Integrated Methodologies for Assessing Particulate Matter (TRANSPHORM)

Start date: Jan 1, 2010, End date: Jun 30, 2014,

TRANSPHORM brings together leading air quality and health researchers and users to improve the knowledge of transport related airborne particulate matter (PM) and its impact on human health and to develop and implement assessment tools for scales ranging from city to Europe. Over four years, TRANSPHORM will aim to develop and implement an integrated methodology to assess the health impacts of PM a ...
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 21

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NO-dependent protein translocation and S-nitrosylation of nuclear proteins in Arabidopsis thaliana (PRONITROARAB)

Start date: May 1, 2012, End date: Apr 30, 2014,

"During the last two decades nitric oxide (NO) has emerged as a new chemical messenger in plant biology, which is involved in regulation of many different physiological processes, such as plant defense, transpiration and gas exchange, seed germination, and root development. It is common that many of the biological functions of NO arise as a direct consequence of chemical reactions between proteins ...
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Elaboration and refinement of sensorineural dendritic architecture (SENSORINEURAL)

Start date: Sep 1, 2008, End date: Feb 28, 2014,

"Vertebrate sensory perception and integration depend on the formation of ordered connections between sensory neurons and their target cells that occur along several steps: a- establishment of cellular identity, b- neuronal axon growth, arborization and dendritogenesis, c- somatodendritic contact and synaptic refinement. Although there is a wealth of information about the molecular mechanisms cont ...
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 3

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Development of rehabilitation technologies and approaches for multipressured degraded waters and the integration of their impact on river basin management (AQUAREHAB)

Start date: May 1, 2009, End date: Dec 31, 2013,

Within the AQUAREHAB project, different innovative rehabilitation technologies for soil, groundwater and surface water will be developed to cope with a number of hazardous (nitrates, pesticides, chlorinated and aromatic compounds, mixed pollutions,…) within heavily degraded water systems. The technologies are activated riparian zones/wetlands; smart biomass containing carriers for treatment of wa ...
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Environmental Chemoinformatics (ECO)

Start date: Oct 1, 2009, End date: Sep 30, 2013,

"The implementation of the new EU legislation concerning the registration, evaluation, authorization and restriction of chemicals (REACH) requires demonstration of the safe manufacture of chemicals and their safe use throughout the supply chain. REACH encourages development of new in vitro test methods and replacement of animal tests wherever possible by alternative methods. These goals are not ac ...
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 7

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Fluorescence intraoperative imaging platform for tumor margin delineation (FI2P4TUM)

Start date: Jul 1, 2011, End date: Jun 30, 2013,

"According to the World Health Organization (WHO), cancer is a leading cause of death worldwide. Among the distinct types of cancer treatments, surgery, which is the oldest modality, is still often confronted with difficulties in the identification of cancer spread and the accurate delineation of tumor margins. This is of uttermost importance in order to infer the lowest harm to the organ where th ...
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