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The European Commission has identified the challenge of population ageing as the most pressing policy issue in the 21st century. As Europeans live longer and disabilities in this population increase, valid and comparable longitudinal data on their health is essential for evidence based policy making. Valid data requires better measurement instruments and methodologies for longitudinal and cross-po ...

Neuropsychiatric disorders affect 25% of the population sometime during their life. Aberrant dendritic arbors appear in mental disorders. Although the psychopathological mechanisms are not completely understood, it has been suggested that changes in gene expression contribute to the development and therapy. Several evidences, including the applicant own studies, suggest that misregulation of Sp4 t ...