2 European Projects Found
Searched on 125080 European Projects
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Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems (DETECTIVE)
Start date: Jan 1, 2011, End date: Dec 31, 2015,
"Assessment of repeated dose toxicity is a standard requirement in human safety evaluation and relies on animal testing as no alternatives are currently accepted for regulatory purposes. An integrated research strategy for the replacement of animal tests needs to comprise the development of biomarkers of long-term toxicity in human target cells. To this aim, the DETECTIVE project will set up a scr ...
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Embryonic Stem cell-based Novel Alternative Testing Strategies (ESNATS)
Start date: Apr 1, 2008, End date: Sep 30, 2013,
"ESNATS aims at developing a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs). ESNATS will address current drug-testing shortcomings: - testing takes place late in the development cycle - animal test systems bear the risk of non-prediction due to ...
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