4 European Projects Found
Searched on 125080 European Projects
FINISHED
Systems biology of liver cancer: an integrative genomic-epigenomic approach (MODHEP)
Start date: Jan 1, 2011, End date: Jun 30, 2016,
"Cancer is a complex disease involving multiple genetic and epigenetic events occurring, and influencing each other, over a long period of time. Understanding cancer, and ultimately developing effective targeted therapies, will therefore require that mutations and epigenetic alterations be systematically investigated during the multiple stages of disease development, from identifiable pre-neoplast ...
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18
Partners Participants
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European Consortium on Synaptic Protein Networks in Neurological and Psychiatric Diseases (EUROSPIN)
Start date: Jan 1, 2010, End date: Jun 30, 2014,
"Signalling at nerve cell synapses - a key determinant of all aspects of brain function - depends on the function of hundreds of synaptic proteins and their interactions. Numerous recent studies showed that a wide range of neurological and psychiatric diseases are 'synaptopathies' whose onset and progression are due to mutations of synaptic proteins and subsequent synaptic dysfunctions. EUROSPIN w ...
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19
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BrainTrain: Integrative neuroscience school on brain function and disease (BrainTrain)
Start date: Nov 1, 2009, End date: Oct 31, 2013,
Brain disorders, in particular neurodegenerative diseases and mental illnesses are among the most prevalent and debilitating diseases. Because they are chronic, quality of life and socio-economic prospects are dramatically impaired. Increased life expectancy further enhances the impact of brain dysfunction on society. In coming decades this burden will grow into one of most pressing and costly pro ...
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14
Partners Participants
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Molecular Networks of Dopaminergic Neurons in Chordates (DOPAMINET)
Start date: Feb 1, 2009, End date: Jul 31, 2012,
"Background. Parkinson Disease is the second most common progressive neurodegenerative disorder. The selective degeneration of subsets of midbrain dopaminergic neurons is believed to be the primary cause for disruption of the ability to control movements. Objective. We propose to apply a highly interdisciplinary approach to construct complex networks consisting of protein coding genes, non-protein ...
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