Search for European Projects

8 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation (INFRAFRONTIER-I3)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:• Develop a series of mutant alleles for every gene in the mouse genome• Determine the phenotypic consequences of each mutation• Identify mouse models for the complete dise ...
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 24

 FINISHED 

EUCOMM: Tools for Functional Annotation of the Mouse Genome (EUCOMMTOOLS)

Start date: Oct 1, 2010, End date: Sep 30, 2015,

The EUCOMMTOOLS Collaborative Project responds to the topic ‘HEALTH.2010.2.1.1-1: Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease.’ EUCOMMTOOLS will provide, in a systematic high-throughput way, genetic tools and resources contributing to the determination of every gene’s function in any cell type of the entire organism at any g ...
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 11

 FINISHED 

Coordinating the cooperation of the ESFRI project Infrafrontier with the International Phenotyping Consortium (IMPC) (INFRACOMP)

Start date: Oct 1, 2011, End date: Sep 30, 2014,

InfraCoMP will establish efficient coordination mechanisms between the ESFRI project Infrafrontier and the International Mouse Phenotyping Consortium. Infrafrontier is a pan-European initative to build a sustainable research infrastructure for systemic phenotyping, archiving and distribution of mouse models of human diseases. The IMPC is a global project to carry out systemic phenotyping of mouse ...
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 9

 FINISHED 

Fighting blindness of Usher syndrome: diagnosis, pathogenesis and retinal treatment (TreatRetUsher) (TREATRUSH)

Start date: Feb 1, 2010, End date: Jan 31, 2014,

Usher syndrome (USH) is the most frequent hereditary cause of deafness associated to blindness. It is a rare disease, affecting 1 in every 10.000 individuals, with an autosomal recessive monogenic inheritance. Deafness is congenital while the retinitis pigmentosa is not detected before the age of 8 to 10. These patients suffer from a dreadful disability as their two major senses are impaired. Impo ...
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 13

 FINISHED 

Servicing the European Biomedical Research Community: Archiving and Dissemination of Mouse Models of Human Disease (EMMAservice)

Start date: Jan 1, 2009, End date: Dec 31, 2012,

The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:1) Develop a series of mutant alleles for every gene in the mouse genome2) Determine the phenotypic consequences of each mutation3) Identify mouse models for the complete d ...
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 11

 FINISHED 

A comprehensive dissection of pneumococcal-host interactions (PNEUMOPATH)

Start date: Mar 1, 2009, End date: Aug 31, 2012,

"This project is a fundamental, comprehensive study of the host-pathogen interactions during infection with Streptococcus pneumoniae. The expectation is that the basic knowledge gained from this work will give new targets for vaccination, diagnosis and treatment. In PNEUMOPATH, academic and industrial partners will work together in six scientific workpackages. 1) The molecular epidemiology of anti ...
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 15

 FINISHED 

Large-scale, high-throughput automated systems for phenotyping mouse models of human disease (PhenoScale)

Start date: Mar 1, 2009, End date: Feb 29, 2012,

We are now entering an era of genomic exploration. The mouse is a pre-eminent model not only to map all mammalian genes, but to determine the function of each of these genes. There are now many large-scale projects to create collections of mutant and knock-out mice. However the next step which will add immense value to these collections will be the determination of the phenotype of each of these m ...
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 5

 FINISHED 

Coordination of resources for conditional expression of mutated mouse alleles (CREATE)

Start date: Nov 1, 2008, End date: Oct 31, 2011,

"This proposal describes CREATE, an internationally based Coordination Action directly addressing a large scale data gathering activity for systematic conditional mouse mutagenesis. Advances in the sophisticated manipulation of the mouse genome has established the mouse as the premier organism for developing models of human disease. Internationally coordinated initiatives have established for the ...
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 8