Search for European Projects

9 European Projects Found

Searched on 125080 European Projects

 FINISHED 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Start date: Jan 1, 2017, End date: Mar 31, 2022,

"The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, Twins ...
Read Project

 16

 FINISHED 

Exploitation of Glycosylation Signatures for Precision Medicine (GlySign)

Start date: Oct 1, 2016, End date: Sep 30, 2020,

GlySign is a research training network for the translation of glycomic clinical biomarkers for Precision Medicine (PM). Complex, distinctive changes occur in the glycomics profiles or - Glycan Signatures - of human glycoproteins during progression of many chronic diseases including cancer and inflammatory conditions. The three beneficiaries of the GlySign Consortium have been instrumental in contr ...
Read Project

 3

 FINISHED 

Exploiting Glycosylation of Colorectal Cancer for the development of improved diagnostics and therapeutics (GlyCoCan)

Start date: Sep 1, 2015, End date: Aug 31, 2019,

Colorectal cancer (CRC) is a major worldwide cancer burden with about 1.4 million cases in 2012 and an annual mortality of approximately 700,000. Early detection is crucial as treatment is most efficient in early stages where population based screenings could substantially reduce incidence and mortality.Current screening techniques are invasive or lack sensitivity and specificity. Moreover, the mo ...
Read Project

 9

 FINISHED 

Multi-dimensional omics approach to stratification of patients with low back pain (PAIN-OMICS)

Start date: Sep 1, 2013, End date: Aug 31, 2018,

"Pain-OMICS is a multidisciplinary consortium of leading clinical, academic and SME researchers in pain and different omics technologies. Genome-wide association studies identified a number of loci associated with pain, but the level of knowledge about underlying mechanisms of different pain syndromes as well as individual variation in the disease course remains inadequate. Pain-OMICS will capital ...
Read Project

 11

 FINISHED 

Methods for high-throughput glycoproteomic analysis (HTP-GlycoMet)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

... fractionation of complex biological fluids (BIA-SEP), (ii) purification of proteins from body fluids and membrane proteins (UNI-RI), (iii) high-throughput glycomic analysis by use of chromatography (Genos) and multiplexed capillary gel electrophoresis (MPI) and (iv) expertise in the field of viral immunology (MEDRI) we can achieve significant progress in this direction. All our partners are recog ...
Read Project

 6

 FINISHED 

Methods for Integrated analysis of Multiple Omics datasets (MIMOmics)

Start date: Oct 1, 2012, End date: Sep 30, 2017,

MIMOmics develops statistical methods for the integrated analysis of metabolomics, proteomics, glycomics and genomic datasets in large studies. Our project is based on our involvement in studies participating in EU funded projects, i.e. GEHA, IDEAL, Mark-Age, ENGAGE and EuroSpan. In these consortia the primary goal is to identify molecular profiles that monitor and explain complex traits with nove ...
Read Project

 15

 FINISHED 

Methods for high-throughput (HTP) analysis of protein glycosylation (HighGlycan)

Start date: Nov 1, 2011, End date: Oct 31, 2016,

Glycosylation is a post-translational modification that enriches protein complexity and function. Dysregulation of glycosylation is associated with a wide range of diseases, including cancer, diabetes, as well as congenital, cardiovascular, immunological and infectious disorders. A number of studies identified potentially important glycan disease biomarkers. With regard to biotechnology, proper gl ...
Read Project

 9

 FINISHED 

Diagnostic and prognostic biomarkers for inflammatory bowel disease IBD-BIOM (IBD-BIOM)

Start date: Oct 1, 2012, End date: Sep 30, 2016,

Inflammatory bowel diseases affect 0.8% of the Europeans, and are associated with high morbidity, definite mortality and an increasing economic burden. Current diagnostic tools and therapeutics for IBD are unsatisfactory. Development of biomarkers allowing insights into pathogenesis, prognosis and targeted therapy is a major unmet need. This programme addresses that need. IBD-BIOM is a multidisci ...
Read Project

 11

 FINISHED 

Tools for the Detection of Novel Glyco-biomarkers (GlycoBioM)

Start date: Jan 1, 2011, End date: Dec 31, 2015,

Glycosylation patterns on glycoproteins and glycolipids are involved in the regulation of inter- and intracellular recognition events and alteration of such glycosylation has been observed in many diseases, notably in a variety of cancers. We propose that a systematic, large scale investigation in this area will provide a rich spectrum of novel and structurally diverse carbohydrate-based highly sp ...
Read Project

 6