3 European Projects Found
Searched on 125080 European Projects
FINISHED
Identification and therapeutic targeting of common arrhythmia trigger mechanisms (EUTRIGTREAT)
Start date: Oct 1, 2009, End date: Mar 31, 2015,
Arrhythmias are common manifestations of heart disease which frequently cause sudden cardiac death (SCD) or other devastating health problems. In Europe, prevention of SCD by device and drug therapy is expensive and increasingly strains public health resources due to a growing population at risk. However, identification of patients at increased risk for SCD is ineffective, and SCD prevention strat ...
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15
Partners Participants
FINISHED
HUMAN INDUCED PLURIPOTENT STEM CELLS AS A MODEL TO STUDY METABOLIC INHERITED LIVER DISEASES (IPSMILD)
Start date: Dec 1, 2011, End date: Nov 30, 2014,
"Familial hypercholesterolemia type IIa (FH) is a life-threatening disease caused by mutations on the Low Density Lipoprotein Receptor (LDLR). While drug treatments reduce the level of circulating cholesterol in heterozygote patients (1:500) with variable efficiency, homozygote patients (1:106) can only be treated by bimonthly apheresis, an invasive procedure. Hepatocytes are the only cells capabl ...
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1
Partner Participant
FINISHED
Personalised and intergrated cardiac care: \nPatient-specific Cardiovascular Modelling and Simulation for In Silico Disease Understanding and Management (euHeart)
Start date: Jun 1, 2008, End date: Nov 30, 2012,
Cardiovascular disease (CVD) has a significant impact on the European society in terms of mortality, morbidity and allied healthcare costs. The opportunity of multi-scale modelling spanning, sub-cellular level up to whole heart is to improve CVD outcomes by providing a consistent, biophysically-based framework for the integration of the huge amount of fragmented and inhomogeneous data currently av ...
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