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Vertebrate heart morphogenesis is a complex process that integrates different structures and cell types compelled to interact by genetic and epigenetic factors. Mistakes at any step from cell-commitment to valve formation will have a major impact on heart morphogenesis leading to congenital heart disease. Avian embryos offer an ideal system to study heart development because the development of th ...

"Recently the zebrafish has emerged as a new important system for cancer research because the zebrafish genome contains all orthologs of human oncogenes and forms tumors with similar histopathological and gene profiling features as human tumors. The zebrafish provides an in vivo vertebrate model for identifying novel mechanisms of cancer progression and for development of new anticancer compounds ...