Search for European Projects

24 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Breast CAncer STratification: understanding the determinants of risk and prognosis of molecular subtypes (B-CAST)

Start date: Sep 1, 2015, End date: Aug 31, 2020,

Breast tumours are heterogeneous, and result from the complex interplay of multiple lifestyle/environmental and genetic risk factors. Through the EU-funded COGS project, we have identified a large number of germline variants that influence the risk of breast cancer. In combination, these variants can identify women at wide ranges of genetic risk, even in the absence of family history of breast can ...
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 13

 FINISHED 

Phylogeography and somatic evolution of cancer tumor cells (PHYLOCANCER)

Start date: Oct 1, 2014, End date: Sep 30, 2019,

"By far, most evolutionary research has focused on the changes that occur in the germline of individuals across generations, within and between species. For different reasons, much less attention has been given to the process of change within the somatic line of a multicellular individual. The formation of cancer tumors due to uncontrolled cell proliferation is one of the most prominent forms of s ...
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 4

 FINISHED 

Dynamics of human genome architecture in stable and transient gene expression changes (4D-GENOME)

Start date: Jun 1, 2014, End date: May 31, 2019,

The classical view of genomes as linear sequences has been replaced by a vision of nuclear organization that is both dynamic and complex, with chromosomes and genes non-randomly positioned in the nucleus. Process compartmentalization and spatial location of genes modulate the transcriptional output of the genomes. However, how the interplay between genome structure and gene regulation is establish ...
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 2

 FINISHED 

RD-CONNECT: An integrated platform connecting registries, biobanks and clinical bioinformatics for rare disease research (RD-CONNECT)

Start date: Nov 1, 2012, End date: Oct 31, 2018,

Despite examples of excellent practice, rare disease (RD) research is still mainly fragmented by data and disease types. Individual efforts have little interoperability and almost no systematic connection between detailed clinical and genetic information, biomaterial availability or research/trial datasets. By developing robust mechanisms and standards for linking and exploiting these data, RD-Con ...
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 30

 FINISHED 

Health and Environment-wide Associations based on Large population Surveys (HEALS)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools th ...
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 37

 FINISHED 

MULTISCALE APPROACH TO THE IDENTIFICATION OF MOLECULAR BIOMARKERS IN ACUTE HEART FAILURE INDUCED BY SHOCK (Shockomics)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

The management of cardiovascular stability in shock patients is of paramount importance in critical care. New, cutting edge knowledge is necessary to overcome the shortcomings of available therapies, in order to cope with the challenges that anesthesiologists, intensive care specialists and emergency physicians face when dealing with shock patients.Current therapies are targeted to reduce symptoms ...
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 11

 FINISHED 

BBMRI - Large Prospective Cohorts (BBMRI-LPC)

Start date: Feb 1, 2013, End date: Jan 31, 2017,

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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 36

 FINISHED 

A BLUEPRINT of Haematopoietic Epigenomes (BLUEPRINT)

Start date: Oct 1, 2011, End date: Sep 30, 2016,

In response to the call for a high impact initiative on the human epigenome, the BLUEPRINT Consortium has been formed with the aim of generating at least 100 reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. BLUEPRINT will focus on distinct types of haematopoietic cells from healthy individuals and o ...
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 45

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Airway Disease PRedicting Outcomes through Patient Specific Computational Modelling (AirPROM)

Start date: Mar 1, 2011, End date: Jun 30, 2016,

The airways diseases asthma and chronic obstructive pulmonary disease affect over 400 million people world-wide and cause considerable morbidity and mortality. Airways disease costs the European Union in excess of €56 billion per annum. Current therapies are inadequate and we do not have sufficient tools to predict disease progression or response to current or future therapies. Our consortium, Air ...
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 40

 FINISHED 

European Sequencing and Genotyping Infrastructure (ESGI)

Start date: Feb 1, 2011, End date: Jul 31, 2015,

The objective of this project is the integration of world class high-throughput sequencing and genotyping facilities that will provide sequencing and genotyping technologies and data analysis methodologies to the scientific community.The European Sequencing and Genotyping Infrastructure (ESGI) will enable external users to generate data rapidly and to acquire knowledge efficiently. By providing ac ...
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 11

 FINISHED 

European Infrastructure of Open Screening Platforms for Chemical Biology (EU-OPENSCREEN)

Start date: Nov 1, 2010, End date: Apr 30, 2015,

The EU-OPENSCREEN Preparatory Phase forms the basis for the construction and operation of a pan-European infrastructure of open screening platforms for Chemical Biology. EU-OPENSCREEN will bring together leading laboratories from 14 European countries covering all aspects of Chemical Biology from high-throughput screening with a dedicated compound library to assay development, chemical synthesis f ...
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 24

 FINISHED 

Monitoring public opinion on Nanotechnology in Europe (NANOPINION)

Start date: May 1, 2012, End date: Oct 31, 2014,

NANOPINION will provide a multi-tasking and enlivening online science-technology-social media-based platform for learning, information, outreach, dialogue and monitoring for young people, general public and consumer opinion on NT, realising the need for enhanced communication and dialogue between science and society for successful technology development and societal acceptance. A central dialogue ...
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 20

 FINISHED 

Sharing capacity across Europe in high-throughput sequencing technology to explore genetic variation in health and disease (GEUVADIS)

Start date: Oct 1, 2010, End date: Dec 31, 2013,

"High-throughput next-generation DNA sequencing technologies allow investigators to sequence entire human genomes at an affordable price and within a short time frame. The correct interpretation, storage, and dissemination of the large amount of produced genomics data generate major challenges. Tackling these challenges requires extensive exchange of data, information and knowledge between medical ...
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 17

 FINISHED 

Membrane Enhanced Tide Synthesis - A New Paradigm Peptide / Oligonucleotide Synthesis Technology (MEMTIDE)

Start date: Dec 1, 2009, End date: Nov 30, 2013,

"The MemTide Initial Training Network will create a new generation of synthesis technologies for peptide and oligonucleotide (“tide”) manufacture, with focus on the use of emerging membrane technology to effect critical separations. New nanofiltration membranes with improved chemical stability, and closely controlled molecular discrimination properties, will be developed. Novel synthesis strategie ...
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 7

 FINISHED 

Finding biomarkers of anti-microbial drug resistance via a systems biology analysis of fungal pathogen interactions with the human immune system (SYBARIS)

Start date: Nov 1, 2009, End date: Apr 30, 2013,

We propose a systems biology study of the specificity of response of the cell-mediated immune system to fungal microorganisms in order to investigate the genetic basis of susceptibility to fungal disease and elucidate molecular mechanisms of drug resistance in fungal pathogens. An integrative approach, combining high-throughput and traditional wet-lab work with computational and bioinformatics met ...
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 9

 FINISHED 

REvolutionary Approaches and Devices for Nucleic Acid Analysis (READNA)

Start date: Jun 1, 2008, End date: Nov 30, 2012,

"The REvolutionary Approaches and Devices for Nucleic Acid analysis – READNA – consortium is composed of researchers from 10 academic institutions, 5 SMEs and 3 large companies. The goals of the READNA consortium are to revolutionize nucleic acid analysis methods, by 1) improving elements necessary to use the currently emerging generation of nucleic acid sequencers in a meaningful and accessible w ...
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 20

 FINISHED 

A European gateway to the science and research of health, through online and offline innovative activities aimed at citizens, patients, pupils and teachers (Xplore Health)

Start date: Jan 1, 2010, End date: Aug 31, 2012,

Xplore Health is a joint initiative to build and promote an online and offline interactive environment – with multimedia tools and attending activities – that will nurture active engagement of society with state-of-the-art science and research around health and its wider ethical, legal and social aspects (ELSA) by facilitating an effective dissemination of attractive, accessible and rigorous resou ...
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 5

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Targeting Protein Synthesis in the Apicoplast and Cytoplasm of Plasmodium (MEPHITIS)

Start date: Jan 1, 2009, End date: Jun 30, 2012,

"The protein synthesis machinery represents one of the most useful targets for the development of new anti-infectives. Several families of broadly used antibiotics (tetracyclines, macrolides, and novel glycopeptides like vancomycin, among others) exert their function by blocking the protein synthesis machinery. Doxicycline, a tetracycline antibiotic, remains a useful tool for the prevention of pal ...
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 9

 FINISHED 

IT Future of Medicine (ITFoM)

Start date: May 1, 2011, End date: Apr 30, 2012,

Data-rich, individualised medicine poses unprecedented challenges for IT, in hardware, storage and communication. We propose a data-driven, individualised medicine of the future, based on molecular/physiological/anatomical data from individual patients. We shall make general models of human pathways, tissues, diseases and ultimately of the human as a whole. Individualised versions of the models, ...
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 25

 FINISHED 

Markers for emphysema versus airway disease in COPD (EvA)

Start date: Oct 1, 2008, End date: Mar 31, 2012,

COPD is characterized by emphysema (destruction of the lung alveoli) and airway disease (inflammation and thickening of the bronchial wall) both of which lead to airway obstruction. These two features co-exist in most patients but some patients present with only emphysema (E) or only airway disease (A). The aim of the project is to identify markers specific to E and A of COPD. Our hypothesis is th ...
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 15

 FINISHED 

Coopération transnationale pour l'innovation technologique dans le développement de molécules pour le traitement de l'obésité et du diabète (DIOMED)

Start date: Mar 31, 2009, End date: Mar 30, 2012,

DIOMED pretende contribuir a hacer frente a las barreras que limitan el desarrollo del sector biomédico en la zona SUDOE. El proyecto impulsará la transferencia de conocimiento e innovaciones de la universidad a la empresa lo que ayudará a acortar el tiempo para lograr la convergencia con el resto de Europa en cuanto a impacto económico y creación de empleo en sectores sector de ciencias de la vid ...
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 6

 FINISHED 

Communicating NANOtechnology to European YOUth (NANOYOU)

Start date: Apr 1, 2009, End date: Jun 30, 2011,

NANOYOU will design and undertake a communication and outreach program in nanotechnology (NT) aimed at European youth. The project will reach 11-18 year olds through school programs to take place in at least 20 EU Member States and Associated States. Additional programs aimed at young adults aged 19-25 will be offered in science centres. The school programs are planned to involve at least 400 scho ...
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 9

 FINISHED 

European network of regional projects for school partnerships on climate change research (CARBOSCHOOLS+)

Start date: Jan 1, 2008, End date: Dec 31, 2010,

CarboSchools+ proposes to link carbon science laboratories with secondary schools to develop partnerships where young Europeans learn and conduct experiments about climate research and reduction of greenhouse gas emissions. In partnership projects, scientists and teachers co-operate over several months to give young people a practical experience of research through real-time experiments, site visi ...
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 11

 FINISHED 

Best Practices for IPR and Technology Transfer in Nanotechnology Developments (Nano2Market)

Start date: Jul 1, 2009, End date: Aug 31, 2010,

The lack of models for technology transfer at nanotechnology developments is of increasing concern for the sector. This CSA will fulfil this gap providing guidelines for technology transfer and rules for IPR and license agreements in nanotechnology developments. To achieve these objectives, a consortium is formed by: 1) Key European research centres in different areas of nano and converging techno ...
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 10