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Structural studies of Nucleotide Excision Repair complexes (NERCOMP)

Start date: Jan 1, 2012, End date: Dec 31, 2017,

"DNA damage caused by chemical and physical factors can lead to detrimental effects to the cell and must be corrected. One of the primary pathways to achieve this repair is nucleotide excision repair (NER). In NER, the DNA damage is first located, a stretch of bases harboring the lesion is removed, and the gap is filled by a DNA polymerase. The unique feature of NER is its ability to correct a wid ...
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