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Studying Physiology and Pathology of Imprinted Genes to understand the role of Epigenetic Mutations in Human Disease (INGENIUM)
Start date: Apr 1, 2012, End date: Mar 31, 2016,
"The aim of this ITN is to promote research and training in the field of epigenetics associated with human disease. Expression of imprinted genes is mono-allelic and gamete of origin-dependent. This is due to different epigenetic modifications present on the maternal and paternal chromosomes. Failure in normal establishment, maintenance or erasure of these marks results in gene dosage dysregulatio ...
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