Search for European Projects

11 European Projects Found

Searched on 125080 European Projects

 FINISHED 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Start date: Oct 1, 2013, End date: Mar 31, 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
Read Project

 44

 FINISHED 

Protein S-mycothiolation and real-time redox imaging in Corynebacterium diphtheriae during ROS stress and infection conditions (MYCOTHIOLOME)

Start date: Apr 1, 2014, End date: Mar 31, 2019,

Glutathione serves as the major thiol-redox buffer in the defense against Reactive Oxygen Species (ROS) in eukaryotes. Firmicutes bacteria utilize as thiol redox buffer bacillithiol (Cys-GlcN-Mal, BSH) and Actinomycetes produce the related redox buffer mycothiol (AcCys-GlcN-Ins, MSH). In eukaryotes, proteins are post-translational modified to S-glutathionylated proteins in response to oxidative st ...
Read Project

 2

 FINISHED 

Synthesis of mono-dithiolene molybdenum complexes and their evaluation as potential drugs for the treatment of human isolated sulfite oxidase deficiency (MOCOMODELS)

Start date: Feb 1, 2012, End date: Jan 31, 2018,

Two rare but usually fatal diseases are caused by a failure at different levels of the multistep biosynthetic generation of the three human molybdenum dependent enzymes involved in metabolic processes. In contrast to the more general Moco deficiency (MocoD) affecting all three enzymes, isolated sulfite oxidase deficiency (iSOD) cannot be treated yet. The proposed project is primarily aimed at synt ...
Read Project

 3

 FINISHED 

Creating Economic Space for Social Innovation (CRESSI)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

"The CRESSI project will explore the economic underpinnings of social innovation with a particular focus on how policy and practice can enhance the lives of the most marginalized and disempowered citizens in society. Overall, the bid will take an institutionalist view of the key issues exploring the drivers and structures that lead to marginalization and disempowerment and then setting out how int ...
Read Project

 9

 FINISHED 

Oral biopharmaceutics tools (ORBITO)

Start date: Oct 1, 2012, End date: Sep 30, 2017,

The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
Read Project

 28

 FINISHED 

Advanced Multidisciplinary Training in Molecular Bacteriology (AMBER)

Start date: Jan 1, 2013, End date: Dec 31, 2016,

"The advancement in life sciences has created a growing number of disciplines that are required to elucidate the increasingly complicated biological questions. This has led to an unsurpassed level of knowledge, but it has also resulted in a continuous specialization in PhD trainings, which makes the students less prepared for complex present day biological questions. To provide a better comprehens ...
Read Project

 9

 FINISHED 

Nanoelectronic COupled Problems Solutions (nanoCOPS)

Start date: Nov 1, 2013, End date: Oct 31, 2016,

Designs in nanoelectronics often lead to problems that are large to simulate and that include strong feedback couplings. Industry demands to include variability to guarantee quality and yield. It also requests to incorporate higher abstraction levels to allow for system simulation in order to shorten design cycles, while preserving accuracy. The nanoCOPS project considers the simulation of two pro ...
Read Project

 13

 FINISHED 

An interactive protein engineering portal with validated software and database facilities (NEWPROT)

Start date: Dec 1, 2011, End date: Nov 30, 2015,

Two academic groups and eight SMEs who all work on different aspects of protein engineering will collaborate and produce a website that will consist of a portal with an embedded workbench to provide users a self-service system for in silico protein engineering. This interactive self-service portal will give users access to a wide variety of protein engineering facilities and information systems, a ...
Read Project

 10

 FINISHED 

MOTivational strength of ecosystem services and alternative ways to express the value of BIOdiversity (BIOMOT)

Start date: Sep 1, 2011, End date: Aug 31, 2015,

People in Europe acknowledge that nature is important to them and to society at large. Economists have shown that indeed, biodiversity has total economic values running into the trillions of euros worldwide and hundreds of millions even for ‘minor’ ecosystem services on local scales. In spite of these immense values, politicians and the general public in Europe do not appear to really act for natu ...
Read Project

 8

 FINISHED 

"CATO - CBRN crisis management: Architecture, Technologies and Operational Procedures" (CATO)

Start date: Jan 1, 2012, End date: Dec 31, 2014,

"CATO proposes to develop a comprehensive Open Toolbox for dealing with CBRN crises due to terrorist attacks using non-conventional weapons or on facilities with CBRN material. CATO will:• combine CBRN knowledge, planning & response know-how, DSS building blocks and dedicated models and algorithms• enable the development of specific holistic CBRN-DSS• cover the entire CBRN disaster life cycle from ...
Read Project

 28

 FINISHED 

European Network on Directed Evolution of Functional Proteins (ENEFP)

Start date: Oct 15, 2008, End date: Oct 14, 2012,

"This project intends to use directed evolution as tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. By harnessing the forces of Darwinian evolution in the laboratory we want to (i) screen large and diverse genome libraries for protein with new and useful functions, (ii) optimize existing proteins for appl ...
Read Project

 10