5 European Projects Found
Searched on 125080 European Projects
FINISHED
Post-infectious immune reprogramming and its association with persistence and chronicity of respiratory allergic diseases (PreDicta)
Start date: Oct 1, 2010, End date: Mar 31, 2016,
Chronic inflammatory diseases associated with allergy, including asthma and rhinitis, constitute a major and continuously growing public health concern for Europe. However, the causative factors and mechanisms converting a physiological inflammatory reaction to a chronic response triggering allergic disease remain elusive.Viral infections, particularly those caused by human rhinoviruses (RV) are t ...
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13
Partners Participants
FINISHED
Towards a Clean, Litter-Free European Marine Environment through Scientific Evidence, Innovative Tools and Good Governance (CLEANSEA)
Start date: Jan 1, 2013, End date: Dec 31, 2015,
There is an urgent need for an improved knowledge base for the management of marine litter. CLEANSEA aims to generate new information on the impacts (biological, social and economic) of marine litter, develop novel tools needed to collect and monitor litter and protocols needed for monitoring data (litter composition and quantities) and evaluate the impact of mitigation strategies and measures in ...
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18
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Mechanisms of the Development of ALLergy (MEDALL)
Start date: Dec 1, 2010, End date: May 31, 2015,
Causes explaining the epidemic of IgE-associated (allergic) diseases are unclear. MeDALL (Mechanisms of the Development of Allergy) aims at generating novel knowledge on mechanisms of allergy initiation, in particular in childhood. To understand how a complex network of genetic and environmental factors leads to complex allergic phenotypes, a novel stepwise, large and integrative translational app ...
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24
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"Fungi in the setting of inflammation, allergy and autoimmune diseases:Translating basic science into clinical practices" (ALLFUN)
Start date: Dec 1, 2010, End date: May 31, 2014,
"The ALLFUN proposal aims at defining the cellular and molecular mechanisms by which ubiquitous airborne or commensal fungi contribute to immune homeostasis and its dysregulation leading to allergy and inflammatory diseases. Breakthroughs in understanding how mucosal homeostasis is established, maintained or disrupted in the presence of fungi should be sources of new therapeutic targets and drugs ...
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14
Partners Participants
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Signaling Mechanisms Intersecting Histamine Receptors and Pattern Recognition Receptor Activation in Dendritic Cells (DC-Signal)
Start date: Jun 1, 2011, End date: May 31, 2013,
The immune response is a tightly regulated process which normally results in protection from infection and tolerance of innocuous environmental antigens. However, in allergy and asthma, the activated immune response results in a chronic pro-inflammatory state characterized by T cell Th2 polarization to normally well-tolerated antigens resulting in tissue inflammation and tissue remodeling. Dendr ...
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