6 European Projects Found
Searched on 125080 European Projects
FINISHED
Bioactivated hierarchical hydrogels as zonal implants for articular cartilage regeneration (HYDROZONES)
Start date: Jan 1, 2013, End date: Dec 31, 2017,
Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects.Current cartilage implants cannot establish th ...
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18
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FINISHED
RADical reduction of OXidative stress in cardiovascular diseases (RADOX)
Start date: Jan 1, 2013, End date: Dec 31, 2016,
Cardiovascular disease (CVD) constitutes a major and increasing health burden in developed countries. The prediction is that the prevalence of these conditions will increase by ~60% over the next 20 years. Therefore, the development of novel treatments for patients with CVD becomes more and more urgent. Oxidative stress is an important molecular contributor to the pathogenesis of CVD. However, ox ...
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10
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Transposon-based, targeted ex vivo gene therapy to treat age-related macular degeneration (AMD) (TARGETAMD)
Start date: Nov 1, 2012, End date: Oct 31, 2016,
Age-related Macular Degeneration (AMD), a neurodegenerative disease of the retina, is a major cause of blindness in elderly people. Due to the aging population, AMD has been referred to as a “time bomb” in society. In the exudative form of AMD, high levels of vascular endothelial cell growth factor (VEGF) and low levels of pigment-epithelial derived factor (PEDF), an inhibitor of vascularization a ...
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16
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Selection and improving of fit-for-purpose sampling procedures for specific foods and risks (BASELINE)
Start date: Aug 1, 2009, End date: Nov 30, 2013,
"Food Safety Objectives (FSO) and Performance Objectives (PO) are new criteria complementing the existing concepts of microbiological criteria and MRL for many chemical contaminants. However, to achieve these objectives it is critically important a harmonisation of food safety control procedures.BASELINE project intends to obtain the following objectives: 1) To review the sampling schemes currentl ...
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20
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European Network for Cell Imaging and Tracking Expertise (ENCITE)
Start date: Jun 1, 2008, End date: Nov 30, 2012,
"Cell therapy can be defined as the transplantation of living cells for the treatment of medical disorders. Three different principles underlie the increasing interest in cell therapy. 1. Transplanted cells used as an “active drug” 2. Transplanted cells used to replace damaged and degenerated tissue. 3. Cells used as a drug delivery vehicle. Promising results have been obtained in pre-clinical and ...
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30
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Therapy after heart infarct: prevention of reperfusion injury and repair by stem cell transfer (Infarct Cell Therapy)
Start date: Jan 1, 2009, End date: Jun 30, 2012,
A key problem in repair and functional regeneration following myocardial infarction is the inability of heart muscle tissue to regenerate itself and appropriate vascularization under conditions of increased strain caused by the reduced contractibility of the damaged heart. This frequently leads to continuous loss of functional cells, further increase of the infarct area and finally complete loss o ...
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