Search for European Projects

Over 40 European Projects Found

Searched on 125080 European Projects

 FINISHED 

A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients (MERCURIC)

Start date: Dec 1, 2013, End date: Nov 30, 2020,

Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less than 5% because of ineffective treatments. Increased understanding of cancer biology, coupled with the implementation of “omi ...
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 13

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Frontiers in Quantum Materials Control (Q-MAC)

Start date: Oct 1, 2013, End date: Sep 30, 2019,

The overarching goal of the present proposal is to exploit materials design, coherent optical methods and multiple theoretical approaches to deterministically control ordered states of strongly correlated electron materials, also referred to as “quantum” or “complex” materials. The underlying ideas can be applied to vast number of problems in materials physics, but the stated goal is that of optim ...
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 4

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The Developing Human Connectome Project (dHCP)

Start date: Sep 1, 2013, End date: Aug 31, 2019,

Few advances in neuroscience could have as much impact as a precise global description of human brain connectivity and its variability. Understanding this ‘connectome’ in detail will provide insights into fundamental neural processes and intractable neuropsychiatric diseases.The connectome can be studied at millimetre scale in humans by neuroimaging, particularly diffusion and functional connectiv ...
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 4

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Platform foR European Preparedness Against (Re-)emerging Epidemics (PREPARE)

Start date: Feb 1, 2014, End date: Jan 31, 2019,

Far from receding, the threats posed by infections with epidemic potential grow ever greater. Although Europe has amongst the best healthcare systems in the world, and also the world’s supreme researchers in this field, we lack co-ordination and linkage between networks that is required to respond fast to new threats. This consortium of consortia will streamline our response, using primary and sec ...
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 27

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DIabetes REsearCh on patient sTratification (DIRECT)

Start date: Feb 1, 2012, End date: Jan 31, 2019,

The overarching aims of the DIRECT consortium, consisting of 20 leading academic groups in diabetes and 5 EFPIA companies, are to identify biomarkers that address current bottlenecks in diabetes drug development and to develop a stratified medicines approach to treatment of type 2 diabetes with either existing or novel therapies.There is heterogeneity in who develops diabetes, the rate at which th ...
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 27

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Targeted Action for Curing Trauma Induced Coagulopathy (TACTIC)

Start date: Nov 1, 2013, End date: Oct 31, 2018,

"Trauma remains one of the world’s biggest contributors to the global burden of disease. Predominantly affecting young adults and children, 800,000 European injury related deaths were recorded in 2002. Outcomes for critically injured trauma patients remain poor with severe bleeding, brain injury and tissue damage being associated with high mortality and disability. Nearly half of all trauma fatali ...
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 9

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Cognitive Biases - Windows into the Mechanisms underlying Emotional Vulnerability and Resilience (CogBIAS)

Start date: Oct 1, 2013, End date: Sep 30, 2018,

"Every person responds to life's difficulties in different ways. But why do some 'suffer the slings and arrows of outragerous fortune' and other 'take arms against a sea of trouble'. There are those who are vulnerable and fragile, falling prey to anxiety, depression and a range of compulsions that, left unattended, can easily turn into addicitons. Then there are the those who irrespective of what ...
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 1

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Targeting and exploiting B cell functions for treatment in cardiovascular disease (Athero-B-Cell)

Start date: Sep 1, 2013, End date: Aug 31, 2018,

Cardiovascular disease (CVD) mortality and morbidity is predicted to increase in Europe and worldwide in the next decades due to aging and the rise of diabetes and obesity. The link between metabolic and inflammatory disease is getting stronger, raising hopes for novel therapeutic targets to be exploited clinically. Clinical evidence generated by the Academic partners of the Athero-B-Cell Consorti ...
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 11

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Targeting novel lipid pathways for treatment of cardiovascular disease (Athero-Flux)

Start date: Sep 1, 2013, End date: Aug 31, 2018,

Lipid lowering has significantly reduced cardiovascular disease (CVD) mortality in EU. However, the aim to abolish CVD in EU is far from achieved and attempts to improve on the benefits of statins with new agents have not yet delivered new therapeutics. The Consortium Athero-Flux builds on FP7-generated large-scale lipidomics data showing that specific sphingolipids and in particular distinct cer ...
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 12

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Preventing Abuse of Children in the Context of AIDS in sub-Saharan Africa (PACCASA)

Start date: Jun 1, 2013, End date: May 31, 2018,

"To date, 12 million children have been orphaned by AIDS, and 70 million more live with AIDS-affected caregivers within sub-Saharan Africa. Our programme of research has demonstrated heightened levels of physical, sexual and emotional abuse amongst children in AIDS-affected families. Despite increasing calls for intervention studies addressing child abuse in the developing world (UN 2008; WHO 2010 ...
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 1

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Improving Prostate Cancer Outcome with Vectored Vaccines (IMPROVE)

Start date: Apr 1, 2014, End date: Mar 31, 2018,

A successful vaccine against cancer is most likely to work through the induction of potent CD8+ T cells that can successfully kill tumour cells. But achieving this has proved difficult and only low level responses are induced by current vaccine approaches. Nonetheless, two therapeutic immunisation strategies have shown partial success in targeting prostate cancer, and one recently reached licensur ...
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 5

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Assessment of the impact of drivers of change on Europe's food and nutrition security (TRANSMANGO)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

TRANSMANGO aims to obtain a comprehensive picture of the effects of the global drivers of change (climate, economic concentration and market structure, financial power, resource competition, marginalization, property rules, geo-political shifts, consumer preferences, consumption patterns and nutritional transition) on European and global food demand and on raw material production (and, consequent ...
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 13

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industry-Academia Research on Three-dimensional Image Sensing for Transportation (IARTIST)

Start date: Feb 1, 2014, End date: Jan 31, 2018,

An industry academic partnership project to enhance research and knowledge transfer in the field of three dimensional image processing for transportation industry.
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 4

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Economic Modeling for Climate-Energy Policy (ECOCEP)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

"Climate change is one of the most challenging and important problems facing European and world society. Our project concentrates on several key aspects of climate change economics, including the valuation of climate change impacts, the main determinants of key drivers of climate change, the economic impact of climate change mitigation policies and the examination of climate change related risks, ...
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 4

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Indo European Collaboration on Moduli Spaces (MODULI)

Start date: Jan 1, 2014, End date: Dec 31, 2017,

"This proposal is concerned with a joint Indo-European presearch programme on the field of moduli spaces. Moduli spaces are basic and central objects that emerge in the most natural classification problems in geometry. Their importance has been emphasized over the years due to the relation of these spaces with areas of mathematics so diverse as algebraic geometry, differential geometry, topology, ...
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 4

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Freezing Colloids (FREECO)

Start date: Jan 1, 2012, End date: Dec 31, 2017,

The freezing of colloids is an amazingly common phenomenon encountered in many natural and engineering processes such as the freezing of soils, food engineering or cryobiology. It can also be used as a bioinspired, versatile and environmentally-friendly processing route for bioinspired porous materials and composites exhibiting breakthroughs in functional properties. Yet, it is still a puzzling ph ...
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 2

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Impact of Biogenic versus Anthropogenic emissions on Clouds and Climate: towards a Holistic UnderStanding (BACCHUS)

Start date: Dec 1, 2013, End date: Nov 30, 2017,

Clouds are a very important, yet not well understood feedback factor in climate change and they contribute to the effective radiative forcing (ERF) from aerosol-cloud interactions (ACI). The uncertainty in ERFaci is larger than for any other forcing agent. Also, feedbacks between the terrestrial and marine biosphere and the atmosphere involving ACI are thought to play an important role in regulati ...
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 22

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Cold Molecular Ions at the Quantum Limit (COMIQ)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

"COMIQ (COld Molecular Ions at the Quantum limit)will investigate how cooling, trapping, and control techniques applied molecular ion can expand the realm of quantum technology, enhance precision meaurements on molecular systems and lead to chemistry at the ultracold quantum limit."
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 10

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European Research Infrastructures for Poverty Related Diseases (EURIPRED)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

HIV/AIDS, Tuberculosis (TB) and Malaria alone account for more than six million deaths worldwide every year. Despite substantial efforts made in recent years, Poverty Related Diseases are still spreading. New therapeutic interventions are therefore urgently required to combat Poverty Related Diseases. The existence of a well-developed HIV/TB/Malaria infrastructure presents a prime opportunity to a ...
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 18

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PHYSICAL ACTIVITY THROUGH SUSTAINABLE TRANSPORT APPROACHES (PASTA)

Start date: Nov 1, 2013, End date: Oct 31, 2017,

This project focuses on the systematic promotion and facilitation of active mobility (AM) (i.e. walking and cycling including the combination with public transport use) as an innovative approach to integrate physical activity (PA) into individuals’ everyday lives. In contrast to sports or exercise, AM requires less time and motivation, since AM provides both convenience as a mode of transport, and ...
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 18

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Individualised Diagnostics and Rehabilitation of Attention (INDIREA)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

"We propose a training network based around a linked set of research projects which attempt to improve the diagnosis and rehabilitation of neuropsychological disorders of attention, with each project linked to an external industrial partner in order to commercialise emerging diagnostic and rehabilitation procedures. New diagnostic procedures will link clinical measures of attentional disorders to ...
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 8

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Power and Region in a Multipolar Order (PRIMO)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

"PRIMO (Power and Regions in a Multipolar World) starts from the premise that the importance of non-western regions and certain of their leading states – notably Brazil, Russia, India, China and South Africa, the so-called BRICS states – for international politics and the world economy is rapidly growing. However, the nature of these processes, the consequences for global governance, and the mater ...
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 11

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Advanced Immunization Technologies (ADITEC)

Start date: Oct 1, 2011, End date: Sep 30, 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

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ADvanced Electric Powertrain Technology (ADEPT)

Start date: Oct 1, 2013, End date: Sep 30, 2017,

The goal of the ADEPT program is to produce a virtual development environment for E-propulsion systems and to train and establish a multi-disciplinary research network. The ADEPT program will raise the profile and to improve career perspectives for 12 ESRs, and 2 ERs, offering a high-quality structured consortium providing personalized training opportunities in E-propulsion systems and in compleme ...
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 12

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Macroeconomics and Financial History (MACROHIST)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

"The current macroeconomic and financial crisis has given rise to a vigorous debate about the state of macroeconomics and macroeconomic training. Among the voices arguing most strongly for a change in the way that young macroeconomists are trained are those coming from employers in the private and public sector. Strikingly, many employers are also arguing that a knowledge of economic history might ...
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 7

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Improving the Physics in Ice Sheet Models (ImPISM)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

The aim of this project is to generate new understanding of glacier and ice-sheet dynamics. Specifically, it will improve theoretical models of the physical processes occurring at the base of the ice, and develop the means to integrate these into large-scale simulations used to forecast ice melting and sea level rise. This will provide a vital step forward in the capabilities of these models to ...
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 1

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Digital Scholarly Editions Initial Training Network (DiXiT)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

The Digital Scholarly Editions Initial Training Network (DiXiT) is concerned with one of the most dynamic and pioneering research areas at the intersection of the humanities and computer sciences focused on digital scholarly editions. While the digital turn has challenged the theoretical understanding of and the methodological approach to the core research activity in most of the humanities, there ...
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 10

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Photonic Integrated Compound Quantum Encoding (PICQUE)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

"Quantum information was born from the merging of information science and quantum physics. Its main objective consists of harnessing the quantum nature of information and learning how to process it by using physical systems operating according quantum mechanics laws. Being supported by numerous proofs-of-principle, the field is now ready to proceed to move to the next level of applications, where ...
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 10

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Nano -structural and -dynamic events in the T-cell activation (nanodynaTCELLvation)

Start date: Sep 1, 2013, End date: Aug 31, 2017,

The organization of the T-cell in its resting and activated state, specifically of plasma-membrane molecules involved in the triggering of the T-cell, is a long-standing and contentious research topic in molecular immunology. Understanding the molecular mechanisms involved at the nanoscale, i.e. at spatial scales below the resolution limit of conventional optical microscopy (< 200 nm) will find an ...
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 2

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Low Emissions Core-Engine Technologies (LEMCOTEC)

Start date: Oct 1, 2011, End date: Jun 30, 2017,

The main objective of the LEMCOTEC project will be the improvement of core-engine thermal efficiency by increasing the overall pressure ratio (OPR) to up to 70 leading to a further reduction of CO2. Since NOx increases with OPR, combustion technologies have to be further developed, at the same time, to at least compensate for this effect. The project will attain and exceed the ACARE targets for 20 ...
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 39

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Advanced materials and devices for hybrid spin coherent technologies (ASCENT)

Start date: Dec 1, 2011, End date: Jun 30, 2017,

The property of spin has been harnessed in an array of revolutionary technologies, from nuclear spins in magnetic resonance imaging to spintronics in magnetic recording media. Nature at its deepest level is quantum mechanical and spins are capable of demonstrating superposition and entanglement, yet such coherent properties have not yet been fully exploited. The exquisite control over materials fa ...
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 2

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The genetic basis of meningococcal and other life threatening bacterial infections of childhood (EUCLIDS)

Start date: Dec 1, 2011, End date: May 31, 2017,

Bacterial infection is the major cause of disability and death in children worldwide. We will use meningococcal disease (MD) as a model to understand genetic factors underlying susceptibility and severity of childhood bacterial infection which will then be applied to other childhood infections. We have established cohorts of patients with MD in Central and Southern Europe (CE,SE), UK and Africa as ...
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 16

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BeTheCuRE (BTCURE)

Start date: Apr 1, 2011, End date: Mar 31, 2017,

BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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 41

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Resistance in Gram-Negative Organisms: Studying Intervention Strategies (R-GNOSIS)

Start date: Oct 1, 2011, End date: Mar 31, 2017,

Antibiotics are a mainstay of public health, but their use has increased exponentially leading to the emergence of antibiotic resistance. The R-GNOSIS (Resistance in Gram-Negative Organisms: Studying Intervention Strategies) project combines 5 international clinical studies, all supported by highly innovative microbiology, mathematical modelling and data-management, to determine - in the most rele ...
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 27

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Exploitation of genomic variants affecting coronary artery disease and stroke risk for therapeutic intervention (CVGENES-AT-TARGET)

Start date: Oct 1, 2013, End date: Mar 31, 2017,

Atherosclerosis and its most disabling sequelae, coronary artery disease (CAD) and stroke, are leading causes of death in Europe. Until now, preventive and therapeutic interventions for these diseases aim at ameliorating the effects of established cardiovascular risk factors. More recently, results of genome-wide association (GWA) studies added to our perception of mechanisms leading to atheroscle ...
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 13

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International Research Consortium on Dengue Risk Assessment, Management, and Surveillance (IDAMS)

Start date: Sep 1, 2011, End date: Feb 28, 2017,

The overall concept of this research project is to assemble a consortium of international experts working together to develop new and innovative tools to be applied to the control of dengue in a global context. The core of the application focuses on parallel strategies aimed at:• improving diagnosis and clinical management of dengue through two linked work packages designed a) to identify readily ...
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 18

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EUropean CLimate and weather Events: Interpretation and Attribution (EUCLEIA)

Start date: Nov 13, 2013, End date: Jan 1, 2017,

Climate change is expected to impact extreme weather in Europe. There is therefore a clear need to adapt effectively to climate change, particularly in Europe, where recent heatwaves, floods and droughts have demonstrated the vulnerability of European citizens to extreme weather. However, scientifically robust information about the extent to which recent extreme weather can be linked to climate va ...
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 11

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3to4: Converting C3 to C4 photosynthesis for sustainable agriculture (3TO4)

Start date: Jan 1, 2012, End date: Dec 31, 2016,

Most plants use the C3 pathway of photosynthesis that is compromised by gross inefficiencies in CO2 fixation. However, some plants use a super-charged photosynthetic mechanism called C4 photosynthesis. The C4 pathway is used by the most productive vegetation and crops on Earth. In addition to faster photosynthesis, C4 plants demand less water and less nitrogen. Overall, our aim is to introduce the ...
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 20

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A European Platform for Translational Cancer Research (EUROCANPLATFORM)

Start date: Jan 1, 2011, End date: Dec 31, 2016,

Europe has a number of advantages as regards developing translational cancer research, yet there is no clear European strategy to meet the increasing burden posed by cancer. The FP6 Eurocan+Plus project analysed the barriers underlying the increasing fragmentation of cancer research and stressed the need to improve collaboration between basic/preclinical and comprehensive cancer centres (CCCs), in ...
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 29

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European Clinical trials in Rare Sarcomas within an integrated translational trial network (EUROSARC)

Start date: Dec 1, 2011, End date: Nov 30, 2016,

Sarcomas are rare malignant tumors, with an overall incidence of 6/105/year. Bone and soft tissue connective tissue tumours encompass more than 50 different rare histotypes and more than 150 different molecular subtypes. The incidence of individual rare sarcomas subtypes is often less than 0.5/105/year. Given sarcoma rarity as a group, but even more as individual entities, few prospective clinical ...
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