5 European Projects Found
Searched on 125080 European Projects
FINISHED
The influence of environmental factors on antimicrobial activity of human intestinal defensins (Defensinactivity)
Start date: Feb 1, 2013, End date: Jan 31, 2018,
Human epithelia are permanently challenged by microorganisms. In the gut, the fraction of strict anaerobic bacteria increases from proximal to distal, reaching 99% of bacterial species in the colon. Moreover, microbial metabolism causes a reduction of the environment to a low redox potential of only –200 mV to –300 mV. Defensins, characterised by three intramolecular disulfide-bridges, are key eff ...
Read Project
2
Partners Participants
FINISHED
New Models for Preclinical Evaluation of Drug Efficacy in Common Solid Tumours (PREDECT)
Start date: Feb 1, 2011, End date: Apr 30, 2016,
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
Read Project
23
Partners Participants
FINISHED
Prevention of Falls Network for Dissemination (ProFouND)
Start date: Mar 1, 2013, End date: Feb 29, 2016,
Description
The Prevention of Falls Network for Dissemination (ProFouND) is a thematic network working with the European Innovation Partnership on Active and Healthy Ageing to bring about the dissemination and implementation of best practice in falls prevention across Europe. ProFouND comprises 21 partners from 12 countries, with associate m ...
Read Project
22
Partners Participants
FINISHED
Efficacy and Safety of Inhaled Budesonide in Very Preterm Infants at Risk for Bronchopulmonary Dysplasia (NEUROSIS)
Start date: Mar 1, 2009, End date: Aug 31, 2015,
HYPOTHESIS: Early inhalation of Budesonide (BS) reduces the absolute risk of developing bronchopulmonary dysplasia (BPD) or death in preterm infants born between 23 and 27 weeks gestational age (GA) by 10%. PRIMARY OBJECTIVE: Survival without BPD at 36 weeks GA. SECONDARY OBJECTIVES: (1) neurodevelopment at a corrected age of 18-22 months; (2) adverse treatment effects; (3) mortality at 36 weeks G ...
Read Project
15
Partners Participants
FINISHED
FAll Repository for the design of Smart and sElf-adaptive Environments prolonging INdependent livinG (FARSEEING)
Start date: Jan 1, 2012, End date: Mar 31, 2015,
Description
FARSEEING wants to provide an information basis for research and therapy development for fall prediction, prevention and support, by building the world’s largest fall repository. This database will facilitate the collection, analysis and processing of behavioural and physiological data related to falls, daily activity and physiol ...
Read Project
