6 European Projects Found
Searched on 125080 European Projects
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Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)
Start date: Jan 1, 2015, End date: Dec 31, 2019,
Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
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34
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CO-OPTION OF THE NKG2D LYMPHOCYTE RECEPTOR AS AN ONCOPROTEIN PROMOTING CANCER STEM CELL TRANSDIFFERENTIATION AND CANCER AUTONOMY (NKG2D)
Start date: Jan 1, 2014, End date: Jan 1, 2018,
The stimulatory NKG2D lymphocyte receptor expressed on natural killer cells and T cells and its tumor-associated ligands enable the immune system to recognize and destroy cancer cells. This role of NKG2D is well recognized and efforts are underway to target NKG2D and its ligands for cancer therapy. However, cancers adopt diverse strategies to safeguard their survival. With advanced human cancers, ...
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1
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Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure (OptimEx)
Start date: Oct 1, 2013, End date: Mar 31, 2017,
More than 14 million Europeans suffer from heart failure (HF), of which more than 50 % have HF with preserved left ventricular (LV) ejection fraction (EF) (HFPEF, “diastolic heart failure”). HFPEF is the only cardiovascular disease with increasing prevalence and incidence, affecting 10-20% of the elderly and contributing substantially to hospitalizations of elderly HF patients. Currently, no medic ...
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9
Partners Participants
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Semantic Data Platform for Healthcare (SEMCARE)
Start date: Jan 1, 2014, End date: Dec 31, 2015,
The aim of SEMCARE is to build a semantic data platform to support clinical trials. The platform will identify patient cohorts based on patient-level criteria (e.g. age, gender, diagnosis, indication, symptoms, lab results) scattered in heterogeneous clinical data. As most of patient-level data is unstructured, language technologies are necessary to extract and exploit the relevant data. Our platf ...
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5
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Semantic Interoperability for Health Network (SemanticHealthNet)
Start date: Dec 1, 2011, End date: May 31, 2015,
SemanticHealthNet will develop a scalable and sustainable pan-European organisational and governance process for the semantic interoperability of clinical and biomedical knowledge, to help ensure that EHR systems are optimised for patient care, public health and clinical research across healthcare systems and institutions.Through a clinically-driven workplan, exemplified in cardiovascular medicine ...
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18
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Impact of surgical and pharmacological interventions on fetal lung growth in pulmonary hypoplasia (IncreaseLungGrowth08)
Start date: Dec 15, 2009, End date: Dec 14, 2012,
Pulmonary hypoplasia is a significant cause of perinatal death and occurs with an incidence of 15%. A common (1:2500 newborns) malformation resulting in hypoplastic lungs is congenital diaphragmatic hernia (CDH). Affected lungs have reduced and functionally altered airways and vessels, leading to respiratory deficiency and pulmonary hypertension in the neonatal period. Nowadays, prenatal fetoscopi ...
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