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A detailed understanding of human biology will require characterisation of the human-associated microorganisms, the human microbiome, and of the roles these microbes play in health and disease. Large projects in Europe, the United States, China and Canada target these objectives, using high throughput –omics approaches. Given the complexity of our microbial communities, composed of thousands of ...

A detailed understanding of human biology will require not only knowledge of the human genome but also of the human metagenome, defined here as the ensemble of the genomes of human-associated microorganisms. Our proposal focuses on the microorganisms of the gut, which are particularly abundant and complex and have an important role for human health and well-being. We shall implement and integrate ...