3 European Projects Found
Searched on 125080 European Projects
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European Prevention of Alzheimer’s Dementia Consortium (EPAD)
Start date: Jan 1, 2015, End date: Dec 31, 2019,
Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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Aetionomy – Organising Mechanistic Knowledge about Neurodegenerative Diseases for the Improvement of Drug Development and Therapy (AETIONOMY)
Start date: Jan 1, 2014, End date: Dec 31, 2018,
IMI’s Call 8 is geared to develop knowledge frameworks for ‘druggable mechanisms’ for two domains of pathophysiology. In response to this call, we propose (I) the development of a generic AETIONOMY pipeline to capture and infer over mechanistic knowledge of pathophysiology, and (II) the focused application of this pipeline to derive clinically significant mechanistic taxonomies of neurodegenerativ ...
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20
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Multiregional rtfMRI Neurofeedback for the Prevention of Alzheimer's Disease (NPAD)
Start date: May 1, 2016, End date: Apr 30, 2018,
This project aims at predicting early cognitive decline using a neurofeedback performance endophenotype based on realtime functional magnetic resonance imaging in a population at risk for Alzheimer’s Disease (AD). It has been proven that AD biomarkers change decades before the development of symptoms. In addition, there is a lack of robust hypersensitive methods capable of predicting impending cog ...
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